Effects of nutritional intervention on nutritional status and physical and psychological healthy states in head and neck cancer
patients under radical chemoradiotherapy
1Department of Pain Air Force Hospital of the Eastern Theater of the People's Liberation Army of China Nanjing 210002 Jiangsu
China
2Department of Oncology Nanjing Drum Tower Hospital Affiliated Hospital of Nanjing University Medical School Nanjing
210008 Jiangsu China
3Department of Oncology Air Force Hospital of the Eastern Theater of the People's Liberation Army of China
Nanjing 210002 Jiangsu China
4Department of Clinic Nutrition Nanjing Drum Tower Hospital Affiliated Hospital of Nanjing University Medical School Nanjing 210008 Jiangsu China
Abstract：Objective To explore the effects of nutritional status and physical and psychological healthy state in head and neck
cancer patients with nutritional interventions by dietitians. Method Seventy-two patients with head and neck cancer admitted to Nanjing Drum Tower Hospital Tumor Center from June 2018 to December 2019 were selected. According to the elimination criteria there
were 61 patients randomized to either the control n = 29 or the intervention group n = 32 finally. The control group was treated with
the general nutritional intervention method. In the intervention group patients adopted with diagnosis and treatment model of nutritional
intervention by dietitians. Then the nutrient intaking nutritional indexes the degree of pain and quality of life were compared between the two groups. Result The energy and protein intaking of the two groups were decreased but the intervention group was better
P<0. 05 . In terms of pain psychology and quality of life the VAS and GAD-7 and KPS scores of the intervention group were better
P<0. 05 Except for C-reactive protein the indexes of weight skeletal muscle serum total protein and serum albumin in the intervention group were better P<0. 05 . Conclusion In the treatment of head and neck cancer the mode of clinical nutrition support diagnosis and treatment mode involving dietitians may help to alleviate the deterioration of patients' the physical and psychological healthy
states in addition it may also has advantages in improving the indexes of nutritional status.
基金资助:南京市卫生科技发展专项资金重点项目(ZKX18025)
通讯作者:
王淑安,电子邮箱: glyywsa@163.com
引用本文:
1郑 延,2王孔成,3徐 磊,2汪 娟,4王淑安. 营养干预对头颈部肿瘤患者放化疗期营养及身心状态的影响
[J]. 肿瘤代谢与营养电子杂志, 2022, 9(3): 345-349.
1Zheng Yan，2Wang Kongcheng，3Xu Lei，2Wang Juan，4Wang Shu′an. Effects of nutritional intervention on nutritional status and physical and psychological healthy states in head and neck cancer
patients under radical chemoradiotherapy. Electron J Metab Nutr Cancer, 2022, 9(3): 345-349.
