Abstract：Objective To investigate the correlation between nutritional status and quality of life in esophageal tumors and head and neck tumors during intensity-modulated radiotherapy. Methods The cancer patients who received radiotherapy from November 2018 to May 2019 were selected for the study. NRS 2002 and PG-SGA were used to evaluate the nutrition of the patients during radiotherapy, and EORTC QLQ-C30 was used to evaluate the quality of life, and the correlation between them was analyzed. ResultsA total of 41 patients were enrolled, including 23 cases of esophageal cancer and 18 cases of head and neck cancer. 35 cases （85.36%） lost weight after radiotherapy, of which 19 cases （46.34%） lost ≥ 5% body weight. There were 2 patients with weight loss>10%, accounting for 4.88%, and the average weight loss was 3.6kg. During radiotherapy, there were 31 patients with myelosuppression, 15 patients with hypoalbuminemia and 24 patients with electrolyte disorder. After radiotherapy, The scores of general health status and physical function of patients were lower than those before radiotherapy （P<0.05）. The scores of pain, fatigue and loss of appetite were higher than those before radiotherapy （P<0.05）. General health status, physical function, pain and loss of appetite were significantly correlated with nutritional status （P<0.05）, while social function, emotional function, shortness of breath, constipation showed no significant correlation with nutritional status （P>0.05）. ConclusionThe nutritional status of cancer patients during radiotherapy is correlated with their quality of life. Attention should be paid to the nutritional evaluation and intervention during radiotherapy, in order to improve the quality of life in terms of physical function, pain and appetite and efficacy of cancer patients.
梁岚青， 罗燕容， 王倩倩， 马林， 曲宝林， 刘芳. 调强放疗的肿瘤患者营养状况与生活质量相关性分析[J]. 肿瘤代谢与营养电子杂志, 2019, 6(4): 482-487.
LIANG Lan-qing, LUO Yan-rong, WANG Qian-qian, MA Lin, QU Bao-lin, LIU Fang . Correlation between nutritional status and quality of life during intensity-modulated radiotherapy in cancer patients. Electron J Metab Nutr Cancer, 2019, 6(4): 482-487.
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