Abstract:Objective To investigate the clinical effect of Reyanbao on local pain caused by intravenous infusion drugs. Methods 76 patients with local pain caused by drugs during intravenous infusion were selected and randomly divided into 2 groups (38 patients each): the experimental group (Reyanbao group) and the control group (hot water bag group). VAS scores of patients in the experimental group and the control group before and after treatment were recorded. ResultsThere was a statistical difference in VAS scores between the experimental group and the control group at T2 and T3(P<0.05). VAS scores of the experimental group decreased significantly at T1, T2 and T3(P<0.05). VAS scores of the control group decreased significantly at T1, T2 and T3(P<0.05). There were statistically significant differences in patient satisfaction scores between the experimental group and the control group(P<0.05). In terms of the survey of patients treatment satisfaction, the treatment satisfaction of the experimental group was significantly higher than that of the control group (P<0.05).There were no significant differences in the incidence of adverse events between the two groups (P>0.05).ConclusionReyanbao has a good analgesic effect on local pain caused by intravenous infusion drugs.
1张海静,2盛崴宣,1刘金霞,2关雷. 中药热奄包治疗输注性疼痛的临床效果研究[J]. 肿瘤代谢与营养电子杂志, 2019, 6(4): 477-481.
1ZHANG Hai-jing, 2SHENG Wei-xuan,1LIU Jin-xia,2GUAN Lei . Study on the clinical effect of Reyanbao on local pain caused by intravenous infusion drugs. Electron J Metab Nutr Cancer, 2019, 6(4): 477-481.
1.Perinel J, Mariette C, Dousset B, et al. Early enteral versus total parenteral nutrition in patients undergoing pancreaticoduodenectomy. Ann Surg. 2016;264(5):731-737.
2.Zeng S, Xue Y, Zhao J, et al. Total parenteral nutrition versus early enteral nutrition after cystectomy:A meta-analysis of postoperative outcomes. Int Urol Nephrol. 2018;51(1):1-7.
3.苏敏慧.论《临证指南医案》“通”法及其应用.辽宁中医药大学学报. 2014;16(1):163-165.
4.Ronen O, Shlomo F, Benadiva G, et al. A prospective clinical trial to assess peripheral venous catheter-related phlebitis using needleless connectors in a surgery department. Am J Infect Control. 2017;45(10):1139-1142.
5.Li GH, Jia YJ, Su S, et al. Evidence-based pharmacy evaluation of Ruyi Jinhuang Powder for treating phlebitis. J Pharm Sci-CHINA. 2012;47(22):1860-1864.
6.Benlabed M, Perez M, Gaudy R, et al. Clinical implications of intravenous drug incompatibilities in critically ill patients. Anaesth Crit Care Pain Med. 2019;38(2):173-180.
7.Demircan M, Gurunluoglu K, Karaman A, et al. Damaging effects of total parenteral nutrition formula on vascular endothelium. J Pediatr Gastroenterol Nutr. 2015;61(4):464-468.
8.Lu Y, Hao C, He W, et al. Experimental research on preventing mechanical phlebitis arising from indwelling needles in intravenous therapy by external application of mirabilite. Exp Ther Med. 2018;15(1):276-282.
9.Brenner GJ, Nemark JL, Raemer D. Curriculum and cases for pain medicine crisis resource management education. Anesth Analg. 2013;116(1):107-110.
10.Dugan S, Le J, Jew RK. Maximum tolerated osmolarity for peripheral administration of parenteral nutrition in pediatric patients.JPEN J Parenter Enteral Nutr. 2014;38(7):847-851.
11.Christensen LD, Holst M, Bech LF, et al. Comparison of complications associated with peripherally inserted central catheters and HickmanTM catheters in patients with intestinal failure receiving home parenteral nutrition. Six-year follow up study. Clin Nutr. 2016;35(4):912-917.
12.Dillon RC, Merchan C, Altshuler D, et al. Incidence of adverse events during peripheral administration of sodium chloride 3%. J Intensive Care Med. 2018;33(1):48-53.
13.Xiaohe Y, Shaojie Y, Mingjie W, et al. Risk factors related to peripherally inserted central venous catheter nonselective removal in neonates. Biomed Res Int. 2018;2018:3769376.
14.Pinto RZ, Maher CG, Ferreira ML, et al. Drugs for relief of pain in patients with sciatica: systematic review and meta-analysis. BMJ. 2012;344:e497.
15.Kohno E, Kanematsu S, Okazaki S, et al. [Methods of preventing phlebitis induced by infusion of fosaprepitant]. Gan to kagaku ryoho. Article in Japanese. 2015;42(3):323-326.
16.马学霞.手部抬高法减轻手背部浅静脉滴注药物所致的疼痛的效果观察.泰山医学院学报. 2009;30(9):714-715.
17.张桂英.静脉补钾引起疼痛的护理方法.中国民族民间医药. 2012;22:142.
18.Zheng GH, Yang L, Chen HY et al. Aloe vera for prevention and treatment of infusion phlebitis. Cochrane Database Syst Rev. 2014;6:CD009162.
19.黄剑.消炎镇痛膏应用于减轻刺激性药物输液过程引发疼痛的临床观察.全科护理. 2011;9(10):2733-2734.
20.Kawazoe H, Sumikawa S, Nakauchi K, et al. Preventive effect of pre-warming, hot compress, and pH adjustment in oxaliplatin-induced venous pain. Int J Clin Pharm. 2017;39(6):1291-1297.
21.洪莉莉. 静脉补钾局部疼痛缓解方法的临床观察.医学理论与实践. 2009;22 (12):1520-1521.
22.彭小英. 手三里穴位按摩在治疗输液疼痛中的应用.实用临床医学杂志. 2011;12(1):126.
23.郑素霞.止痛灵药垫热敷治疗静脉输液疼痛53例效果观察.齐鲁护理杂志. 2008;11(14):124.
24.Sha S, Liu W, Cheng L, et al. [Review of traditional Chinese medicine external applications to treat chemistry phlebitis]. Zhongguo Zhong Yao Za Zhi. 2011;36(18):2592-2594.
25.贺俊娇.麝香止痛膏在治疗输液疼痛中的应用.内蒙古中医药. 2013;17:145.
26.廖惠莲.四子散热奄包预防PTCC置管后机械性静脉炎的效果观察.护理与康复. 2013;12(5):452-453.
27.Wu XF, Yu YJ, Ying LM, et al. Hot compress with Chinese herbal salt packets reducing PICC catheter complications: a randomized controlled trial. Chin J Integr Med. 2018;11:809-814.