Applications of early nutraceuticals support and homemade homogenate diet in patients with severe traumatic brain injury
Objective To discuss the effects of early nutraceuticals support and homemade homogenate diet in patients with severe
traumatic brain injury(sTBI). Methods From January 2018 to June 2019, 84 sTBI patients were selected from the No.2 peoples′
hospital of Yibin and divided into nutraceuticals group and homemade homogenate diet (HDD) group randomly, patients in 2 groups
were fed with off?the shelf nutraceuticals and HHD respectively, the nutritional indexes, adverse reactions/complications, Glasgow
Coma Score (GCS) and hospitalization expenses were observed after 4 weeks. Results ① After nutrition support for 2 weeks or 4
weeks, hemoglobin (HB), albumin (ALB), prealbumin (PA), transferrin (TF), lymphocyte count (LYM), calf circumference (CC) and
triceps skinfold (TSF) in nutraceuticals group were significantly higher than HHD group (besides TF after nutrition support 2 weeks,
P<0.05). ②The incidence of pathoglycemia, diarrhea and total adverse reaction/complications in nutraceuticals group was significantly
lower than HHD group (pathoglycemia: 14.3%：35.7%; diarrhea: 11.9%：40.5%; total incidence: 15.5%：25.0%, P<0.05). ③After
nutrition support 2 weeks and 4 weeks, GCS in nutraceuticals groups were significantly higher than HHD group［2 weeks：(8.88±1.50)
point (7.76±1.72) point；4 weeks：(10.26±2.40) point (8.86±2.14) point，P<0.05］. ④There was no difference of total hospitalization
expenses and daily hospitalization expenses between 2 groups (P>0.05), daily nutrition support cost in nutraceuticals group was higher
than HHD group ［(356.3±43.9) yuan (159.4±39.4) yuan, P<0.05］. Conclusion Compared with homemade homogenate diet,
nutraceuticals support could be more beneficial to promote nutritional status of sTBI patients, reduce the incidence of insulin resistence,
diarrhea or other complications, improve the prognosis of sTBI patients with possible better cost?effectiveness.
Abstract：Objective To discuss the effects of early nutraceuticals support and homemade homogenate diet in patients with severe
traumatic brain injury(sTBI). Methods From January 2018 to June 2019, 84 sTBI patients were selected from the No.2 peoples′
hospital of Yibin and divided into nutraceuticals group and homemade homogenate diet (HDD) group randomly, patients in 2 groups
were fed with off⁃the shelf nutraceuticals and HHD respectively, the nutritional indexes, adverse reactions/complications, Glasgow
Coma Score (GCS) and hospitalization expenses were observed after 4 weeks. Results ① After nutrition support for 2 weeks or 4
weeks, hemoglobin (HB), albumin (ALB), prealbumin (PA), transferrin (TF), lymphocyte count (LYM), calf circumference (CC) and
triceps skinfold (TSF) in nutraceuticals group were significantly higher than HHD group (besides TF after nutrition support 2 weeks,
P<0.05). ②The incidence of pathoglycemia, diarrhea and total adverse reaction/complications in nutraceuticals group was significantly
lower than HHD group (pathoglycemia: 14.3%：35.7%; diarrhea: 11.9%：40.5%; total incidence: 15.5%：25.0%, P<0.05). ③After
nutrition support 2 weeks and 4 weeks, GCS in nutraceuticals groups were significantly higher than HHD group［2 weeks：(8.88±1.50)
point (7.76±1.72) point；4 weeks：(10.26±2.40) point (8.86±2.14) point，P<0.05］. ④There was no difference of total hospitalization
expenses and daily hospitalization expenses between 2 groups (P>0.05), daily nutrition support cost in nutraceuticals group was higher
than HHD group ［(356.3±43.9) yuan (159.4±39.4) yuan, P<0.05］. Conclusion Compared with homemade homogenate diet,
nutraceuticals support could be more beneficial to promote nutritional status of sTBI patients, reduce the incidence of insulin resistence,
diarrhea or other complications, improve the prognosis of sTBI patients with possible better cost⁃effectiveness.
1, 2黄小明，1杜宗汉，1雷艳，3郑丽华，4白亚强. 早期营养制剂与自制匀浆在重型颅脑损伤患者中的应用[J]. 肿瘤代谢与营养电子杂志, 2021, 8(1): 78-81.
1, 2Huang Xiaoming，1Du Zonghan, 1Lei Yan, 3Zheng Lihua，4Bai Yaqiang. Applications of early nutraceuticals support and homemade homogenate diet in patients with severe traumatic brain injury. Electron J Metab Nutr Cancer, 2021, 8(1): 78-81.
