1Department of Geriatrics, West China Hospital, Sichuan University, Chengdu 610041; 2National Clinical Research Center of Geriatrics, West China Hospital, Sichuan University, Chengdu 610041; 3Health Care and Medical Research Center, Sichuan University, Chengdu 610041; 4Department of Senior Ward, China-Japan Friendship Hospital, Beijing 100029, China
Abstract： Abstract: Sarcopenia is a syndrome of age-related progressive and universal reduction and loss of skeletal muscle mass and strength. Sarcopenia is very common in older adults, with approximately 10% of old people aged 60 and above suffering from this syndrome. The risk of clinical adverse events such as disability, quality of life, and death is greatly increased in older adults with sarcopenia. Malnutrition is also a common problem in the old age population. Although older adults with normal nutritional status may also suffer from sarcopenia, studies found that the risk of sarcopenia is further increased in malnourished older adults. In addition, the lack of certain micronutrients has also been found to be associated with the onset of sarcopenia. Given the adverse effects of sarcopenia on the outcome of older adults, more and more researcher are beginning to explore effective interventions for sarcopenia. At present, the interventions for sarcopenia mainly start from the etiology, including exercise intervention, nutrition intervention, hormone supplementation and drug intervention. Nutrient intervention has become a hot topic in recent years. Nutritional interventions for sarcopenia are diverse, including proteins, amino acids, creatine, vitamin D, minerals, and unsaturated fatty acids. This article will review the effectiveness of different nutritional interventions of sarcopenia, and based on the current evidence to propose recommendations for nutritional intervention of sarcopenia.
2019, Vol. 6 
