1Tongji Hospital， Tongji Medical College， HuaZhong University of Science and Technology， Wuhan 430030， Hubei， China；2Beijing Hospital/National Center of Gerontology， Beijing 100730， China；3Peking University People’s Hospital， Beijing 100044， China；4General Hospital of Tianjin Medical University， Tianjin 300052， China；5The First Affiliated Hospital of Jinan University， Guangzhou 510630， Guangdong， China；6The Second Affiliated Hospital of Nanchang University， Nanchang 330006， Jiangxi， China；7The First Affiliated Hospital of Zhengzhou University， Zhengzhou 450052， Henan， China；8Tenth People’s Hospital of Tongji University， Shanghai 200072， China；9Union Hospital， Tongji Medical College， Huazhong University of Science and Technology， Wuhan 430022， Hubei， China；10Chinese Academy of Medical Sciences Cancer Hospital， Beijing 100029， China；11Nanjing Drum Tower Hospital， the Affiliated Hospital of Nanjing University Medical School， Nanjing 210008， Jiangsu， China；12Sichuan Academy of Medical Sciences & Sichuan Provincial People’s Hospital， Chengdu 610072， Sichuan， China；13Peking Union Medical College Hospital， Beijing 100730， China；14The First Affiliated Hospital， Zhejiang University School of Medicine， Hangzhou 310003， Zhejiang， China；15Guizhou Provincial People’s Hospital， Guiyang 550002， Guizhou， China；16Wuhan No. 1 Hospital， Wuhan 430022， Hubei， China；17West China Hospital of Sichuan University， Chengdu 610041， Hubei， China；18Hainan Medical University， Haikou 571199， Hainan， China；19General Hospital of Central War Zone of the Chinese People’s Liberation Army， Wuhan 430070， Hubei， China；20The First Affiliated Hospital of Anhui Medical University， Hefei 230022， Anhui， China；21Renmin Hospital of Wuhan University， Wuhan 430060， Hubei， China；22Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine， Shanghai 200092， China；23the PLA’s 900 Hospital of the Joint Logistics Team， Fuzhou 350025， Fujian， China；24Tangdu Hospital， Fourth Military Medical University， Xi’an 710038， Shanxi， China；25Zhongnan Hospital of Wuhan University， Wuhan 430071， Hubei， China；26Beijing Tsinghua Changgung Hospital， Beijing 102218， China；27Wuhan Children’s Hospital， Wuhan 430015， Hubei， China；28Second Affiliated Hospital， Zhejiang University School of Medicine， Hangzhou 310009， Zhejiang， China； 29Fujian Province Cancer Hospital， Fujian Medical University Affiliated Cancer Hospital，Fuzhou 350014， Fujian， China；30Beijing Youan Hospital， Capital Medical University， Beijing 100069， China；31The First Hospital of Hebei Medical University， Shijiazhuang 050031， Hebei， China；32Beijing Children’s Hospital， Capital Medical University， Beijing 100045， China； 33Liaoning Tumor Hospital，Shenyang 110042， Liaoning， China；34School of Public Health， Zhejiang University， Hangzhou 310058， Zhejiang， China；35The Affiliated Hospital of Qingdao University， Qingdao 266000， Shandong， China；36Daping Hospital， Army Medical University， Chongqing 400042， China；37The General Hospital of Eastern Theater Commander， the Bayi Hospital Affiliated to Nanjing University of Chinese Medicine， Nanjing 210002， Jiangsu， China；38Beijing Shijitan Hospital， Capital Medical University， Beijing 100038， China
摘要复方氨基酸注射液是肠外营养中氮的来源，广泛应用于不能经胃肠道给予或经胃肠道给予不能满足其营养需求的患者，在营养治疗中起重要作用。但目前对于复方氨基酸注射液临床应用的指征、剂型、剂量、时机，国内并无系统的指南或共识。为了进一步规范复方氨基酸注射液的临床应用，中华医学会肠外肠内营养学分会（Chinese Society for Parenteral and Enteral Nutrition，CSPEN）及中国抗癌协会肿瘤营养专业委员会（Chinese Society of Nutritional Oncology，CSNO）组织全国专家，在系统性文献检索的基础上，参考美国肠外肠内营养学会（American Society for Parenteral and Enteral Nutrition，ASPEN）、欧洲临床营养和代谢学会（European Society for Clinical Nutrition and Metabolism，ESPEN）、CSPEN及CSNO指南，结合我国临床实践，经多次交流讨论，达成此共识。包括10条推荐意见，涉及不同患者的蛋白质需要量及氨基酸剂型选择。
Abstract：Compound amino acid injection， as the source of nitrogen in parenteral nutrition， is administrated to patients with compromised gastrointestinal function or whose nutritional needs cannot be satisfied via the GI tract. Therefore， compound amino acid injection is crucial in nutrition therapies. However， a consensus does not exist in China regarding its indications， formulations， dosages， and the timing of administration. Experts in the field are recruited by the Chinese Society for Parenteral and Enteral Nutrition (CSPEN) and the Chinese Society of Nutritional Oncology (CSNO) to formulate a consensus paper. The current paper aims to provide standardized guidance for clinical use of compound amino acid injection. The consensus paper is a composite of systematically reviewing pertinent literature， Chinese clinical practice， and multiple sessions of debate， discussion， and composition， with reference to guidelines from American Society for Parenteral and Enteral Nutrition (ASPEN)， European Society for Clinical Nutrition and Metabolism (ESPEN)， CSPEN， and CSNO. This consensus presents 10 recommendations for protein needs and appropriate compound amino acid injection formulas to serve varied patients.
高纯，李梦，韦军民，李玉珍，田伟军，姜海平，沈威，许爱国，余震，陈东生，陈莲珍，管文贤，江华，李大魁，梅丹，于吉人，赵春临，范伟，胡松，康焰，康维明，吕传柱，刘. 复方氨基酸注射液临床应用专家共识[J]. 肿瘤代谢与营养电子杂志, 2019, 6(2): 183-189.
GAO Chun， LI Meng， WEI Jun-min， LI Yu-zhen， TIAN Wei-jun， JIANG Hai-ping， SHEN Wei， XU Ai-guo， YU Zhen， CHEN Dong-sheng， CHEN Lian-zhen， GUAN Wen-xian， JIANG Hua， LI Da-kui， MEI Dan， YU Ji-ren， ZHAO C. Expert consensus on clinical use of compound amino acid injection. Electron J Metab Nutr Cancer, 2019, 6(2): 183-189.
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