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肿瘤代谢与营养电子杂志
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食管癌患者术后肠道不耐受评价指标及工具应用
食管癌是全球高发生率、高死亡率的消化道恶性肿瘤之一,手术仍为食管癌最主要的治疗手段,肠内营养(EN)为其 术后营养治疗的首选。食管癌患者在术后需经历长时间的EN 并逐步过渡到经口进食,3~9个月重建新的饮食模式,EN 支持成为 大部分食管癌患者术后恢复正常饮食的过渡阶段。但在术后EN 实施过程中患者易发生肠道不耐受,阻碍了营养治疗治疗的顺 利实施,甚有部分患者因此被迫终止营养治疗,对患者的生存质量及预后带来不利影响。目前国内外尚无公认统一的评价指标 及评估工具,研究者大多根据研究对象自行设计,且研究对象主要为重症监护病房(ICU)的危重症早产儿等,缺乏针对食管癌患 者肠道不耐受的评估工具。选择有效的评估指标及工具,可以及时、准确评估肠道不耐受的发生情况及严重程度,减少肠道不耐 受的发生,同时为临床营养治疗方案的完善提供参考。本文综述了食管癌术后EN 治疗患者肠道不耐受的评估指标及工具,旨在 为临床医护人员准确、有效的评估肠道耐受性提供参考。
Research progress on evaluation indexes and application of evaluation tools for postoperative intestinal intolerance in patients with esophageal cancer
Esophageal cancer is one of the malignant tumors of digestive tract with high incidence and mortality worldwide, surgery is still the primary treatment for esophageal cancer, enteral nutrition(EN)is the first choice for postoperative nutritional support. After surgery, patients with esophageal cancer need to undergo a long time of EN support and gradually transition to oral feeding. After 3 to 9 months, the new diet pattern is reconstructed, and enteral nutrition support becomes an important stage for most patients to resume normal diet after surgery. Postoperative EN support in patients with esophageal cancer is prone to intestinal intolerance. It hinders the smooth implementation of nutritional support treatment. Some patients are forced to stop nutritional therapy. It has adverse effects on the quality of life and prognosis of patients. At present, there are no universally recognized and unified evaluation indicators and evaluation tools at home and abroad, and most researchers design their own evaluation tools according to the research objects, and the research objects are mainly in intensive care unit(ICU), critically ill, premature infants and other infants, and there is a lack of evaluation tools for intestinal intolerance in patients with esophageal cancer. The selection of effective assessment indicators and tools can accurately and timely assess the occurrence and severity of intestinal intolerance, reduce the incidence of intestinal intolerance, and provide a reference for the improvement of clinical nutritional support programs. The paper reviews the assessment indicators and tools for intestinal intolerance in patients with postoperative EN support for esophageal cancer, aiming to provide reference for clinical medical staff to accurately and effectively assess intestinal tolerance.