Chen Yongbing, Yu Kaiying, Rao Benqiang, Shi Hanping
Department of Gastrointestinal Surgery, Beijing Shijitan Hospital, Capital Medical University/the Ninth Clinical Medical College of Peking University, Beijing 100038, China
Abstract:Malignant bowel obstruction (MBO) is one of the most common complications of advanced cancer, which seriously influences the quality of life and the survival time of cancer patients. The complexity of malignant tumors lead to the difficulty treatment options for bowel obstruction. Some studies on MBO treatment with conservative medical therapy show some appreciated effects, but there is no consensus. Most of the treatments were given as hospice care. Clinicians should fully consider the benefits and risks of treatment and carefully choose a personalized treatment program in clinical treatment. Based on the recent advances, current status, and our clinical experiences of treating MBO, we proposed a “6-words principal”. It composed of decompression, nourishment, octreotide, steroid, diuretic, peristalsis, which would improve the treatment effect of MBO and brings hope for MBO patients
陈永兵,于恺英,饶本强,石汉平. 癌性肠梗阻内科治疗的“6字方针”[J]. 肿瘤代谢与营养电子杂志, 2020, 7(2): 141-144.
Chen Yongbing, Yu Kaiying, Rao Benqiang, Shi Hanping. “6-word-tenet” for malignant bowel obstruction. Electron J Metab Nutr Cancer, 2020, 7(2): 141-144.
1.GWILLIAM B, BAILEY C. The nature of terminal malignant bowel obstruction and its impact on patients with advanced cancer[J]. Int J Palliat Nurs, 2001, 7(10): 474-481.
2.TUCA A, GUELL E, MARTINEZ-LOSADA E, et al.Malignant bowel obstruction in advanced cancer patients: epidemiology, management, and factors influencing spontaneous resolution[J].Cancer Manag Res, 2012, 4: 159-169.
3.PAUL OLSON T J, PINKERTON C, BRASEL K J, et al.Palliative surgery for malignant bowel obstruction from carcinomatosis: a systematic review[J].JAMA, 2014, 149(4): 383-392.
4.BLAIR S L, CHU D Z, SCHWARZ R E.Outcome of palliative operations for malignant bowel obstruction in patients with peritoneal carcinomatosis from nongynecological cancer[J].Ann Surg Oncol, 2001, 8(8): 632-637.
5.饶本强,石汉平.癌性肠梗阻: 技术、情感和希望的博弈[J].肿瘤代谢与营养电子杂志, 2017, 4(2): 136-143.
6.于世英,王杰军,王金万,等.晚期癌症患者合并肠梗阻治疗的专家共识[J].中华肿瘤杂志, 2007, 29(8): 637-640.
7.LAVAL G, ARVIEUX C, STEFANI L,et al. Protocol for the treatment of malignant inoperable bowel obstruction: a prospective study of 80 cases at Grenoble University Hospital Center. J Pain Symptom Manage, 2006, 31(6): 502-512.
8.RIPAMONTI C I, EASSON A M, GERDES H. Management of malignant bowel obstruction[J]. Eur J Cancer, 2008, 44(8): 1105-1115.
9.犹东,潘志刚.恶性肠梗阻11例临床分析[J].宁夏医学杂志, 2009, 31(7): 630-631.
10.LEGENDRE H, VANHUYSE F, CAROLI-BOSC FX,et al.Survival and quality of life after palliative surgery for neoplastic gastrointestinal obstruction[J]. Eur J Surg Oncol, 2001, 27(4): 364-367.
11.RIPAMONTI C, TWYCROSS R, BAINES M, et al.Clinical-practice recommendations for the management of bowel obstruction in patients with end-stage cancer[J].Support Care Cancer, 2001, 9(4): 223-233.
12.昊铁成,邵永孚.恶性肠梗阻诊治进展[J].国际外科学杂志, 2007, 34(10): 658-659.
13.ANTHONY T, BARON T, MERCADANTE S, et al. Report of the clinical protocol committee: development of randomized trials for malignant bowel obstruction[J]. J Pain Symptom Manage, 2007, 34(1 Suppl): S49-59.
14.DANS M, SMITH T, BACK A, et al. NCCN Guidelines Insights: Palliative Care, Version 2.2017[J]. J Natl Compr Canc Netw, 2017, 15(8): 989-997.
15.TING-HUI JIANG, XIAN-JUN SUN, et al. Percutaneous needle decompression in treatment of malignant small bowel obstruction[J]. World J Gastroenterol, 2015, 21(8):2467-2474.
16.LI D, DU H, SHAO G,et al. Application of small intestine decompression combined with oral feeding in middle and late period of malignant small bowel obstruction[J]. Oncol Lett, 2017, 14(1):180-184.
17.MERCADANTE S, PORZIO G. Octreotide for malignant bowel obstruction: twenty years after[J].Crit Rev Oncol Hematol, 2012, 83(3): 388-392.
18.WATARI H, HOSAKA M, WAKUI Y, et al. A prospective study on the efficacy of octreotide in the management of malignant bowel obstruction in gynecologic cancer[J]. Int J Gynecol Cancer, 2012, 22(4): 692-696.
19.MASSACESI C, GALEAZZI G.Sustained release octreotide may have a role in the treatment of malignant bowel obstruction[J].Palliat Med, 2006, 20(7): 715-716.
20.SHIMA Y, OHTSU A, SHIRAO K,et al. Clinical efficacy and safety of octreotide (SMS201-995) in terminally ill Japanese cancer patients with malignant bowel obstruction[J]. Jpn J Clin Oncol, 2008, 38(5): 354-359.
21.HISANAGA T, SHINJO T, MORITA T, et al. Multicenter prospective study on efficacy and safety of octreotide for inoperable malignant bowel obstruction[J].Jpn J Clin Oncol, 2010, 40(8): 739-745.
22.SHIMA Y, YAMAGUCHI K, MIYATA Y, et al. A clinical study usingoctreotide in relieving gastrointestinal symptoms due to bowel obstruction in a terminally ill cancer patient[J]. Gan To Kagaku Ryoho 2004, 31(9): 1377-1382.
23.DOLAN EA. Malignant bowel obstruction: a review of current treatment strategies[J].Am J Hosp Palliat Care, 2011, 28(8): 576-582.
24.FAINSINGER R L, SPACHYNSKI K, HANSON J,et al. Symptom control in terminally ill patients with malignant bowel obstruction[J]. J Pain Symptom Manage, 1994, 9(1): 12-18.
25.牛洪欣,徐忠法.低位肠癌恶性梗阻微创治疗进展[J].中华结直肠疾病电子杂志, 2013, 2(3): 127-129.
26.王艳,李新,王正珍.体力活动与癌症研究进展[J].北京体育大学学报, 2015, 38(8): 72-79.
27.石汉平.体力活动是防治肿瘤的最佳措施之一[J].肿瘤代谢与营养电子杂志, 2014, 1(3): 14-17.
28.RAY A D, WILLIAMS B T, COOK J L, et al. Respiratory muscle training improves dyspnea and exercise performance in cancer survivors[J]. Medicine and Science in Sports and Exercise, 2015, 47(5suppl): S608.
29.CERESOLI M, COCCOLINI F, CATENA F, et al. Water-soluble contrast agent in adhesive small bowel obstruction: a systematic review and meta-analysis of diagnostic and therapeutic value[J]. Am J Surg, 2016, 211(6): 1114-1125.
30.SYRMIS W, RICHARD R, JENKINS-MARSH S, et al. Oral water soluble contrast for malignant bowel obstruction[J]. Cochrane Database Syst Rev, 2018, 3: CD012014.
31.LEE C, VATHER R, OCALLAGHAN A, et al. Validation of the phase II feasibility study in a palliative care setting: gastrografin in malignant bowel obstruction[J]. Am J Hosp Palliat Care, 2013, 30(8): 752-758.
32.LANEADER A, ANGELOS P, FERRELL BR, et al. Ethical issues in research to improve the management of malignant bowel obstruction: challenges and recommendations[J]. J Pain Symptom Manage, 2007, 34(1 Suppl): S20-S27.
33.SUO T, GU X, ANDERSSON R, et al. Oral traditional Chinese medication for adhesive small bowel obstruction[J]. Cochrane Database Syst Rev, 2012, (5): CD008836.
34.马骏, 霍介格. 恶性肠梗阻的治疗现状与进展[J]. 世界华人消化杂志, 2017, 25(21): 1921-1927.