Effect of a new enteral nutrition formula strengthened with L-carnitine and taurine on patients with lung cancer undergoing
chemotherapy
1Zheng Jing ,2Li Jianjun
1Department of Nutrition Banan Hospital Affiliated to Chongqing Medical University Chongqing 401320 China
2Department of
Cardiothoracic Surgery Banan Hospital Affiliated to Chongqing Medical University Chongqing 401320 China
Abstract：Objective To explore the effect of a novel enteral nutrition formula fortified with L-carnitine and taurine on patients
undergoing chemotherapy for lung cancer to provide clinical practice basis for the development of a novel nutrition formula. Method
Lung cancer patients who were admitted to Banan Hospital Affiliated to Chongqing Medical University from May 2021 to June 2022 were
screened and randomly divided into two groups. The experimental group was given by a novel enteral nutrition formula supplemented
with L-carnitine and taurine and the control group was given by a conventional whole protein enteral nutrition formula. The patients
took 50 g of their own formula three times a day for 12 weeks. The quality of their daily life nutritional status and the incidence of
toxic and side effects during chemotherapy were compared between the two groups pre- and post- treatment. Result A total of 83
patients were involved in the experimental group and 85 patients were involved in the control group. Before treatment there was no
significant statistical difference between the two groups in the scores of quality of life in various fields including body mass index total
serum protein albumin hemoglobin and subjective overall nutrition assessment scale P>0. 05 . After treatment the patients in the
experimental group obtained higher scores in all fields of quality of life. Especially body mass index total serum protein albumin and
hemoglobin were significantly higher than those in the control group. Even the lower all subjective nutrition assessment scale score
was the better nutritional status is. The difference was statistically significant P<0. 05 . The grade of leukocyte toxicity and side
effects in the experimental group were lower than those in the control group the gastrointestinal reaction was smaller and the duration
of malignant vomiting was shorter than that in the control group. The difference was statistically significant P<0. 05 . Conclusion The
novel enteral nutrition formula strengthened with L-carnitine and taurine can be applied to lung cancer chemotherapy patients which is
conducive to improving their quality of life and their nutritional status and reducing the toxic and side effects of chemotherapy.
收稿日期: 2022-07-24
基金资助:重庆市巴南区科学技术局(2021-61)
通讯作者:
李建军,电子邮箱:676349171@ qq. com
引用本文:
1郑 婧,2李建军. 强化左旋肉碱和牛磺酸肠内营养配方对肺癌化疗患者
的影响[J]. 肿瘤代谢与营养电子杂志, 2023, 10(1): 101-106.
1Zheng Jing,2Li Jianjun. Effect of a new enteral nutrition formula strengthened with L-carnitine and taurine on patients with lung cancer undergoing
chemotherapy. Electron J Metab Nutr Cancer, 2023, 10(1): 101-106.
