1Department of Oncology the People??s Hospital of Dujiangyan Dujiangyan 611830 Sichuan China
2Department of Epidemiology and
Statistics College of Public Health Zhengzhou University Zhengzhou 450001 Henan China.
Abstract：Objective To investigate the effect of nutritional intervention compliance on nutritional status and clinical outcome of patients
with malignant tumor with severe malnutrition. Method A retrospective analysis was performed on 506 patients with malignant tumor and
severe malnutrition admitted to the Department of Oncology from April 2019 to June 2021. The patients were screened and evaluated by
nutritional risk screening NRS 2002 tumor nutrition assessment PG-SGA and simple dietary self-assessment tools. Using nutritional
treatment principle of five steps to nutrition diagnosis treatment and curative effect evaluation and follow - up nutrition therapy plan
according to the patients compliance to group 2 weeks after treatment with nutrition to assess patients compliance score < 6 points into poor
compliance group scoring six points into the good compliance group or higher Blood routine albumin prealbumin physical fitness
height weight and other nutritional indicators were monitored in 2 groups. Result After nutritional intervention for tumor patients under 60
years old for two weeks the changes of blood potassium albumin grip strength and weight loss rate in two weeks were better in patients with
good compliance than those with poor compliance all P < 0. 05 . The changes of RBC albumin prealbumin CRP grip strength and twoweek weight loss rate in tumor patients aged 60 years and over after nutritional intervention for two weeks were better in patients with good
compliance than in patients with poor compliance all P < 0. 05 . The physical status score of tumor patients with good compliance 2 2 3
was lower than that of tumor patients with poor compliance 3 2 3 and the dietary score 3 1 3 was higher than that of tumor patients
with poor compliance 2 1 3 . Patients with PS score < 3 points or ≥ 3 points and dietary score < 3 points or ≥ 3 points had better compliance than those with poor compliance in terms of albumin prealbumin grip strength and weight loss rate within two weeks after nutritional
intervention all P < 0. 05 . Conclusion After standardized nutritional therapy patients with malignant tumors with severe malnutrition
showed significant improvement in rapid changes such as albumin and prealbumin moderate changes such as grip strength and weight loss
rate after 2 weeks in patients with good compliance.
收稿日期: 2022-02-03
基金资助:吴阶平医学基金会科研课题(320. 6750. 19001)
通讯作者:
宋春花,电子邮箱:sch16@ zzu. edu. cn
引用本文:
1王 辉,1苏先旭,1胡梦迪,1周星野,2吴甜甜,2宋春花. 重度营养不良恶性肿瘤患者营养干预依从性对营养
状况的影响[J]. 肿瘤代谢与营养电子杂志, 2022, 9(5): 631-638.
1Wang Hui,1Su Xianxu,1Hu Mengdi,1Zhou Xingye,2Wu Tiantian,2Song Chunhua. Effect of nutritional intervention compliance on nutritional status in malignant tumor patients with severe malnutrition. Electron J Metab Nutr Cancer, 2022, 9(5): 631-638.
