Abstract：The cachexia of tumor patient is characterized by skeletal and visceral muscle consumption in cancer patients. It is accompanied or not accompanied by loss of appetite, anorexia, feeling of fullness, weight loss, muscular atrophy, fatigue, anemia, edema, hypoproteinemia and a series of clinical complications. The existence of tumor cachexia makes it difficult for patients to carry out anti-tumor therapy and reduces the survival of patients. Meanwhile, the appearance of clinical complications also seriously reduces the quality of life of them. The morbidity and the mortality of cachexia in tumor patients is high, and it is difficult toreverse once entering the period of cachexia in clinical. Therefore, it can be improved the weight and reduced the muscle loss, alleviated the symptoms of cachexia, improved the quality of life, prolonged the survival and improved the prognosis by the early intervention. Based on the definition of tumor cachexia,starting from the metabolic changes of the three major nutrients, the possible pathogenesis of tumor cachexia is summarized in this manuscript, And then it described the screening, evaluation and diagnosis of tumor cachexia. The treatment strategies and methods are summarized, including nutritional intervention, exercise intervention, psychological intervention and other drug intervention, and so on. The prospect of multidisciplinary treatment (MDT) of tumor cachexia in the future is also discussed. It is expected to provide a new idea and create a new platform for early diagnosis and treatment, prolong survival and improve prognosis of patients with tumor cachexia.
2018, Vol. 5 
