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| Lipid-mobilizing factor/Zn-α2-glycoprotein in cancer cachexia |
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Abstract Abstract: Objective To summarize the function of lipid-mobilizing factor/Zn-α2-glycoprotein in cancer cachexia. Methods The related literatures were reviewed. Results LMF/ZAG can stimulate fat mobilization and triglyceride hydrolysis in adipose tissue directly via GTP dependent cAMP pathway, and accelerate the consumption and oxidation of white adipose tissue, thus playing a vital role in lipid metabolism and energy balance in cancer cachexia. Meanwhile the changes of lipid metabolism induced by LMF/ZAG and their metabolic products have an important influence on the whole body protein and glucose metabolism. Conclusions LMF/ZAG acts as the key factor of fat consumption and plays an important role in the whole material metabolic disorders in cancer cachexia.
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| [1] |
WANG Chao-yun， DU Cheng， GUAN Xin， DU Xiao-wei， XU Zhu-xuan， ZHENG Zhen-dong. Advances in drug therapy for cancer cachexia[J]. Electronic Journal of Metabolism and Nutrition of, 2019, 6(3): 382-385. |
| [2] |
SUN Xue-hua， ZHOU Fu-xiang. Current problems and thinkings on the cancer metabolic modulation therapy[J]. Electronic Journal of Metabolism and Nutrition of, 2019, 6(3): 287-294. |
| [3] |
1，4 SONG Meng-meng，2CHEN Zhe-wen，3 LI Ye，1，4 SONG Chun-hua，5SHI Han-ping，6MIAO Ming-yong. Advances in anti-tumor effect of mannose[J]. Electronic Journal of Metabolism and Nutrition of, 2019, 6(3): 283-286. |
| [4] |
1YAO Ke-qing， 1WANG Su， 1CHEN Shuang， 1SUN Yan-teng， 1LIU Qing-yang， 1CHEN Tao，1LIU Xue-hui， 2CONG Ming-hua. Application of individualized nutrition diagnosis and intervention in patients with advanced cancer[J]. Electronic Journal of Metabolism and Nutrition of, 2019, 6(3): 305-309. |
| [5] |
1，2ZHU Ming-xing， 1WU Chang-peng， 3YIN Liang-yu，1LU Zong-liang， 1LI Na，1LIU Jie， 1GUO Jing， 1XU Hong-xia. L-carnitine improves skeletal muscle cell atrophy of cancer cachexia by regulating lipid metabolism[J]. Electronic Journal of Metabolism and Nutrition of, 2019, 6(3): 320-325. |
| [6] |
ZHANG Xiao-wei， SHI Han-ping. Non-maligment bowel obstruction in the context of advanced cancer[J]. Electronic Journal of Metabolism and Nutrition of, 2019, 6(3): 361-364. |
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2014, Vol. 1 
