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Nutrition on metabolism of endometrial cancer patients with cachexia |
WANG Xiao-hui,SUN Chao |
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Department of Obstetrics and Gynecology, Tangshan People's Hospital, Tangshan 063000, Hebei, China;
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Department of Obstetrics and Gynecology, Tangshan Harbor Economic Development Hospital, Tangshan 063000, Hebei, China |
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Abstract Objective To investigate the metabolic changes of cachexia in women with advanced endometrial cancer by nutritional intervention. Methods70 patients with advanced endometrial cancer cachexia were randomly selected in our hospital from June 2015 to June 2017 were randomly divided into control group and experimental group, the control group using conventional self feeding intervention, the experimental group with nutrition intervention, the nutrition indexes and the metabolism related indexes before and after intervention, and statistical analysis the difference. ResultsAfter comparing the difference between the value of the nutritional indexes of BMI, blood cells, serum albumin, hemoglobin group before and after the intervention was not statistically significant (P>0.05); The experimental group before and after the intervention of the nutrition indexes between the values of the differences were statistically significant (P<0.05). Before the intervention experiment group before intervention and nutritional value index differences between each index value of the control group were not statistically significant (P>0.05), but after the intervention group were significantly higher than the nutritional value index after the intervention control group each index value, the differences were statistically significant (P<0.05). Compared with the control group before and after the intervention of waist circumference, high density lipoprotein, triglyce ride, systolic pressure, diastolic pressure, the difference between the blood glucose index was not statistically significant (P>0.05); The experimental group did each prognostic index for waist circumference, high density lipoprotein, triglycerides, blood glucose levels were significantly higher than the experimental group before the intervention of each index value. The differences were statistically significant (P<0.05), but no statistically significant difference in systolic blood pressure and diastolic blood pressure between the two groups (P>0.05); The experimental group before the intervention of waist circumference, high density lipoprotein, triglyceride, systolic blood pressure, diastolic blood pressure, blood sugar index before and after the difference between the index value of the control group were not statistically significant (P>0.05). Do the test group of prognostic index for waist circumference, high density lipoprotein, triglycerides, blood glucose values were significantly higher than the control group after intervention of each index value, the differences were statistically significant (P<0.05), but the systolic blood pressure and diastolic blood pressure in the stem was not statistically significant differences between prognosis of the experimental group and the control group (P>0.05). ConclusionNutritional intervention can significantly improve the nutritional status and metabolic markers in patients with advanced endometrial cancer cachexia.
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