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Abstract Abstract: Stimulated by growth factors, hormone and other signals, mTOR plays a critical role in regulating cell proliferation
and differentiation. We reviewed and analyzed literatures, then argued that the methylation of key genes in mTOR signaling pathway
could result in abnormal energy metabolism in cancer, producing aerobic glycolysis, and interfering with protein hydrolysis.
Demethylating genes in mTOR signaling pathway, which might be an entry point to reverse the abnormal energy metabolism in
cancer.
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