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| The clinical effect of Shengbai Guben granule in advanced cancer patients |
| Department of Nutrition, 2Department of Nutrition of Pain Management, Tianjin Medical University Cancer Institute and Hospital,National Clinical Research Center of Cancer, Tianjin Key Laboratory of Cancer Prevention and Therapy |
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Abstract Abstract: Objective The aim of this study was to discuss whether Shengbai Guben granule can improve the nutritional status and the degree of fatigue in advanced cancer patients. Methods From February 24, 2015 to June 18, 2016, 37 patients who received pain management and oral Shengbai Guben granule therapy more than 2 weeks were observed. The change of nutritional status and the degree of fatigue were evaluated by BFI-C, MFI, PG-SGA, albumin level, grip strength, and daily intake. Results The mean score of the degree of BFI-C before treatment was 4.57 and the score was 2.26 after treatment, the score has significant difference
(P=0.001). Similarly, the score of the effect of BFI-C after treatment were significant lower than pre-treatment (P=0.001). The score of MFI mental fatigue (P=0.001), brain fatigue (P=0.003) after treatment were also lower than pre-treatment. The PG-SGA score after treatment was also lower than pre-treatment (10.54 versus 12.17, P=0.001). The mean energy intake before treatment and after treatment has significant difference (P=0.000). Conclusions Oral Shengbai Guben granule can relief the degree of fatigue, and increase the energy intake and improve the nutritional status, however, it needs further study.
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