Abstract：Prior to bone marrow transplantation adverse reactions to myeloablative drugs can lead to decreased appetite taste
salivary gland function gastric emptying and intestinal function in patients as well as severe mucosal inflammation and graft versus
host disease GVHD leading to secondary malnutrition. GVHD can directly damage organs and tissues such as the skin liver
mucosa lungs esophagus and musculoskeletal system. Long term use of immunosuppressants to prevent and treat GVHD can lead to
endocrine and metabolic system diseases including insulin resistance abnormal lipid metabolism hypothyroidism or hypogonadism
resulting in malnutrition. Patients with pre-existing malnutrition before transplantation can sustain malnutrition for several years after
receiving allogeneic bone marrow transplantation. Improving the nutritional status of patients through nutritional therapy can not only
reduce the incidence of acute GVHD in transplant patients shorten implantation time but also reduce infection related mortality and
prolong survival.
中国抗癌协会肿瘤营养专业委员会,中华医学会肠外肠内营养学分会. 骨髓移植患者营养治疗专家共识[J]. 肿瘤代谢与营养电子杂志, 2024, 11(1): 56-59.
Chinese Society of Nutritional Oncology， Chinese Society for Parenteral and Enteral Nutrition. Expert consensus on nutritional therapy for patients with bone marrow transplant. Electron J Metab Nutr Cancer, 2024, 11(1): 56-59.
