Abstract：Cancer patients with diarrhea seriously affect their quality of life and treatment effect and even life - threatening.
Diarrhea can be caused by tumor itself but also by various treatments such as radiotherapy and chemotherapy targeted drugs
immunotherapy intestinal infection drugs tumor surgery enteral nutrition and other factors. The clinical manifestations of
tumor-associated diarrhea are mainly divided into the following three types gastrointestinal symptoms systemic intoxication symptoms
and water electrolyte and acid-base balance disorders. Classifying these symptoms as " uncomplicated" or " complex" can help to
determine the appropriate treatments. For patients with uncomplicated tumor - associated diarrhea of grade 1 or 2 and no other
complications conservative treatments such as health education oral rehydration and antidiarrheal therapy is preferred. Complex
tumor-associated diarrhea including grade 1 or 2 diarrhea with risk factors such as moderate to severe cramping ≥ grade 2 nausea
and vomiting fever sepsis gastrointestinal bleeding etc. grade 3 or 4 diarrhea requires hospitalization and further evaluation of
the condition and close monitoring of vital signs and can be actively treated with maintenance basic glucose and electrolyte infusion. A
multidisciplinary team including gastroenterologists should conduct the assessment.
中国抗癌协会肿瘤营养专业委员会,中华医学会肠外肠内营养学分会. 肿瘤相关性腹泻的营养治疗专家共识[J]. 肿瘤代谢与营养电子杂志, 2023, 10(6): 737-741.
Chinese Society of Nutritional Oncology, Chinese Society for Parenteral and Enteral Nutrition. Expert consensus on tumor-associated diarrhea. Electron J Metab Nutr Cancer, 2023, 10(6): 737-741.
