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Current Issue
2015 Vol. 2, No. 1
Published:
1
Clinical estimation of energy expenditure
2015 Vol. 2 (1): 1-4 [
Abstract
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220
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(1284 KB) (
246
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5
Basic principles of oral nutritional supplements
2015 Vol. 2 (1): 5-9 [
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223
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(1855 KB) (
265
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10
Oral enteral nutrition in clinical use
2015 Vol. 2 (1): 10-13 [
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149
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(960 KB) (
252
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14
Oral nutritional supplements in patients undergoing radiotherapy
2015 Vol. 2 (1): 14-18 [
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178
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(928 KB) (
227
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19
Oral nutritional supplements in household cancer patients
2015 Vol. 2 (1): 19-22 [
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159
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(887 KB) (
235
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23
Better or worse: liver carcinoma follow cirrhosis
2015 Vol. 2 (1): 23-25 [
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206
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(794 KB) (
212
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26
Treatment of cancer related anemia
2015 Vol. 2 (1): 26-28 [
Abstract
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219
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(966 KB) (
235
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29
Consensus, Guideline and Standard Five-step therapy of malnutrition
2015 Vol. 2 (1): 29-33 [
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375
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(993 KB) (
510
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34
Prevention and control of cancer: not far from realization-Interpretation of theme in 2015 World Cancer Day
2015 Vol. 2 (1): 34-38 [
Abstract
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218
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(943 KB) (
79
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39
Study on signifcances of EPO in the patients with digestive tracts cancers
Objective To investigate the clinical values of erythropoietin (EPO) in the patients with digestive tracts cancer in Guangdong General hospital. Methods 226 cases of digestive tracts cancer were analyzed, retrospectively. Results There are signifcant differences of EPO between the groups with and without anemia in patients with digestive tracts cancers, while these patients with different degrees of anemia showed signifcant differences in levels of EPO. Conclusions The EPO in patients with IV stage and metastasis usually had higher levels than that of earlier stage and without metastasis.
2015 Vol. 2 (1): 39-41 [
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138
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(1021 KB) (
215
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42
Platycodin D induces growth arrest and cell cycle arrest in prostate cancer
Objective To evaluate the anti-tumor activity and possible mechanism(s) of Platycodin D (PD), a major saponin derived from Platycodin grandi?orum, in human prostate cancer cell lines. Methods Human prostate cancer cell lines (PC3, DU145 and LNCaP cells), and the non-malignant human prostate epithelial cell line, RWPE-1, were exposed to various concentrations of PD to evaluate its cytotoxicity in vitro (via the MTT assay). Cell cycle analysis was indicated by PI staining with ?ow cytometry. Cell cycle-related proteins levels were assessed by Western blotting. Results PD exerted cytotoxicity against three prostate cancer cell lines, PC3 cells, DU145 cells, and LNCaP cells, with half-maximal inhibitory concentrations (IC50) in the range of 11.17 to 26.13 μmol/L. The PC3 cells were the most sensitive to PD. After being treated with PD for 48 hours, the PC3 cells were arrested in the G2/ M phase, and the DU145 and LNCaP cells were arrested in the G0 /G1 phase. Western blotting analysis indicated that PD exposure decreased the levels of cell cycle-related proteins, including E2F1, CDK2, CDK4, CDK6, CyclinD1, Cdc2, CyclinB1. Conclusions PD exhibits signifcant inhibitory activities against prostate cancer cells, which provides a basis for future development of human prostate cancer chemotherapy.
2015 Vol. 2 (1): 42-45 [
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175
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(1062 KB) (
183
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46
Clinical observation of DBC AMP-Ca in the treatment of radiation pneumonitis
Objective To observe the clinical effcacy of DBC AMP-Ca in the treatment of radiation pneumonitis. Methods 30 patients with lung cancer, complicating 2, 3 and 4 degree of radiation pneumonitis were randomly divided into treatment group and control group. Patient in control group were given oxygenaton, glucocorticoid, expectorant, clearing oxygen free radical and antibiotic treatment, while those with more than 3 degree of radiation pneumonitis aminophylline was used. Patients in treatment group received DBC AMP-Ca intravenously based on the treatment of control group. The effects were compared after two weeks. Results The efficiency of DBC AMP-Ca in treatment of radiation pneumonitis is superior to that of control group (P<0.05). Conclusions DBC AMP-Ca is effective for radiation pneumonitis in patients with lung cancer caused by radiotherapy.
2015 Vol. 2 (1): 46-47 [
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236
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(957 KB) (
206
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54
Breakfast: to eat or to skip?
Objective As more people choose to skip breakfast, this study is to evaluate the impact of breakfast skipping (BS) on human health. Methods We collected and analyzed the results from observational studies, RCT studies, meta analysis and other reviews. Results These studies indicated that BS is associated with high risk of type 2 diabetes, high cardiometabolic risk factors, bone mass loss, and dysmenorrhea in young women. It worsens cognitive outcomes in malnourished children and adolescence. Some evidence established a link between obesity and BS, but some authors argued that the proposed effect of BS on obesity has not yet to establish a causal relationship. In the studies we reviewed, the duration of overnight fasting is rarely specifed. Including this factor in the studies might result in different conclusions. Conclusions We would suggest that breakfast is as important as other meals of the day. Well-designed epidemiological studies are needed before we can reach further conclusions.
2015 Vol. 2 (1): 54-60 [
Abstract
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154
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(1005 KB) (
323
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61
Ketogenic diet and cancer treatment
Objective To summarize the various types of ketogenic diet and its research progress in cancer treatment. Methods Related articles were retrieved by searching the pubmed database with the key words “ketogenic diet” and “cancer”. Results The malignant transformed cells were more dependent on glucose supply than their normal counterparts. Ketogenic diet, low in carbohydrate, exerts anti-neoplastic character by inhibiting the tumor-related signal transduction. Conclusions Ketogenic diet, alone or combined with chemo-radio-therapy could hammer tumor growth in rodents, whereas its clinical application warrants large-scale prospective clinical trials
2015 Vol. 2 (1): 61-66 [
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359
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(1080 KB) (
306
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67
Should taurine act as nutritional supplement?
Objective To discuss taurine act as a kind of human nutritional supplements on the role of different diseases by elaborating physiological effects of taurine. Methods We review the domestic and foreign published literature in recent years on the role of taurine, pathological state caused by taurine defciency, and taurine supplementation in human body. Results Taurine is an important biological active substance in human body. It involves in many physiological activities, including binding bile acid, regulating the osmotic pressure, improving in vivo oxidative stress, stabling cell membranes, regulating cellular calcium ion ?ow, acting as neurotrophic and neuroprotective properties and regulation glucose metabolism. Taurine defciency will result in a variety of pathological conditions in human body and lead to exacerbation of original increases. Taurine has been widely used in powdered formulas of infant and enteral nutrition preparation. Conclusions Acting as an important human nutritional supplement, appropriate taurine supplementation may help patients improve the state of oxidative stress, regulate metabolic balance, reduce or delay the progression of lesions. Thus it can facilitate the clinical outcome of patients.
2015 Vol. 2 (1): 67-70 [
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151
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(2375 KB) (
212
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