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2015 Vol. 2, No. 2
Published: 2015-07-09
 
1 Abnormal metabolism of skeletal muscle in cancer patients
2015 Vol. 2 (2): 1-7 [Abstract] ( 203 ) HTML PDF (1131 KB)  ( 202 )
8 Weight loss in cancer patients
2015 Vol. 2 (2): 8-11 [Abstract] ( 198 ) HTML PDF (892 KB)  ( 197 )
12 Management of cancer associated nausea and vomiting
2015 Vol. 2 (2): 12-14 [Abstract] ( 237 ) HTML PDF (848 KB)  ( 200 )
15 Clinical pathway of diagnosis and treatment of cancer-related anorexia
2015 Vol. 2 (2): 15-18 [Abstract] ( 188 ) HTML PDF (1239 KB)  ( 219 )
19 Perioperative nutrition therapy of esophageal cancer
2015 Vol. 2 (2): 19-22 [Abstract] ( 246 ) HTML PDF (1255 KB)  ( 207 )
23 Nutrition therapy of patients receiving radiotherapy
2015 Vol. 2 (2): 23-25 [Abstract] ( 172 ) HTML PDF (850 KB)  ( 230 )
26 Analytic oncology
2015 Vol. 2 (2): 26-30 [Abstract] ( 201 ) HTML PDF (977 KB)  ( 207 )
31 Three stage diagnosis of malnutrition
2015 Vol. 2 (2): 31-36 [Abstract] ( 332 ) HTML PDF (1073 KB)  ( 271 )
37 Guideline for nutrition therapy of gastric cancer patients
2015 Vol. 2 (2): 37-40 [Abstract] ( 386 ) HTML PDF (1012 KB)  ( 510 )
41 Perioperative management of elder patients with colorectal cancer
Objective To investigate the perioperative management of patients over 80 years old with colorectal cancer. Methods From June 2006 to June 2012, clinical data of 41 patients over 80 years old with colorectal cancer was analyzed retrospectively. Results Of all patients, 4 patients underwent emergency operation, 37 patients accepted limited operation. 31 patients underwent radical resection and 9 patients underwent palliative resection, transverse colostomy was performed in 1 patient. 15 patients had complications, 39 patients were healing well completely except that 2 patients died after operation. Conclusions For colorectal cancer patients, old age should not be surgical contraindication. Short-term outcomes will be achieved while paying attention to organ functions especially the cardiorespiratory function and nutritional status controlling surgical trauma and surgical time.
2015 Vol. 2 (2): 41-44 [Abstract] ( 184 ) HTML PDF (964 KB)  ( 201 )
45 Nutrition intervention of different vitamins and minerals proportion during the perioperative period of total gastrectomy
Objective To investigate the clinical effect of the nutrition intervention of different vitamins and minerals proportion during the perioperative period of total gastrectomy. Methods 21 cases total gastrectomy for gastric cancer patients were divided into three groups and all patients started early enteral nutrition support on the frst days after operation. Group A,B,C were respectively treated with high, middle and low vitamin and minerals proportion nutritional support, and the body weight, hemoglobin, prealbumin, plasma protein, liver and kidney function, blood glucose, electrolytes, exhaust time before and after nutrition support were recorded. Results 21 cases with no death , no serious complications, liver and kidney function had no change during the study. Nutritional index of group A was superior to that of groups B, C and have no statistical difference with the preoperative nutritional level. Conclusions Effect of a few mineral with a large number of vitamins used in nutrition support can achieve better, and suitable for nursing and treatment in operation period of total gastrectomy
2015 Vol. 2 (2): 45-47 [Abstract] ( 241 ) HTML PDF (998 KB)  ( 212 )
48 Study on the effcacy of oral bile in patients with hilar cholangiocarcinoma
Objective? ?To evaluate the effectiveness and nursing method of pre-operation oral bile in patient of hilar cholangiocarcinoma. Methods 80 patients’ clincal datum of hilar cholangiocarcinoma in Biliary Tract Surgery Dept 1 from August 2012 to January 2014 were collected, all of the patients accepted percutaneous transhepatic choledochus drainage (PTCD) before abdominal operation. According to exclusion criteria, 7 patients was not included in the analysis. According to oral bile or not, those patients were divided into two groups, the treatment group (PTCD+oral bile, n=39) and the control group (PTCD only, n=34). 5 days after PTCD, oral bile began in the treatment group. The serum test (liver function and electrolytes) was performed on day 5, day 8 and day 12 after PTCD. At the same time point, the bile ?ux, the transfusion volume, and the quantity of potassium supplement in 24 hours were recorded. The patients’ symptoms of anorexia or not were also recorded. χ2 test, t test and repeated measures were used to do the statistical analysis. Results After oral bile: (1)Appetite improvement rate, the treatment group increased signifcantly than the control group day 8 (P=0.009) and day 12 (P=0.001) after PTCD. In treatment group, 10 patients (10/39) had mild stomach discomfort, 3 patients (3/39) had mild distention. After psychological care and oral method of adjusting, the 13 patients tolerated the oral bile. (2) The serum total protein (P=0.017) and prealbumin (P=0.019) , the treatment group also increased signifcantly than the control group, while, the decrease rate of serum total bilirubin had no signifcant difference (P=0.989). (3)The transfusion volume (P=0.017) and supplement of potassium (P=0.011) the treatment group decreased signifcantly than the control group. Conclusions Compared with the only PTCD, PTCD combined with oral bile, was a kind of better method for pre-operation preparation in patient of hilar cholangiocarcinoma. PTCD combined with oral bile not only reduced the amount of transfusion and the supplement of potassium, but also signifcantly improved the nutritional situation of the patients.
2015 Vol. 2 (2): 48-51 [Abstract] ( 232 ) HTML PDF (1061 KB)  ( 197 )
57 Clinical supplementation of β-hydroxy-β-methylbutyrate and its mechanisms
Objective To review recent clinical literatures on the effectiveness of HMB supplementation in pathological conditions. Methods Utilizing electronic online database search using the keyword HMB, then screened, compared and summarized the results of HMB supplementation. Results β-hydroxy-β-methylbutyrate is a metabolite of the essential amino acid leucine. Plenty of researches show that HMB may have the effect in preventing muscle wasting and increasing muscle mass, and has been widely used in sports and body building. Many diseases, such as severe trauma, cancer, AIDS, the elderly muscle atrophy may lead to muscle wasting. Therefore, HMB is also used in clinical treatment for muscle wasting in the past few years. Conclusions Although there are discrepancies among the results of different studies, HMB supplementation has been shown its increase effect on lean body mass in the most of literatures. Consequently, HMB supplementation attenuates muscle wasting and reduces the risk of poor prognosis. It may due to the complex metabolism of HMB.
2015 Vol. 2 (2): 57-62 [Abstract] ( 266 ) HTML PDF (1231 KB)  ( 267 )
63 Ghrelin and Ghrelin mimetics in cancer-related anorexia and cachexia syndrome
Objective Cancer-related anorexia and cachexia syndrome (CACS) is a kind of complex clinical syndrome with a high mortality in advanced stage of cancer. Ghrelin and Ghrelin mimetics have showed excellent effect and tolerance in latest studies. In this paper, we review the present situation and the progress in studies about the effect of Ghrelin, Ghrelin mimetics and related growth factors in CACS. Methods Related articles were obtained through comprehensive search in the database, like CNKI, Pubmed, and so on, with the keywords “cancer, cachexia, Ghrelin, Ghrelin mimetics, growth hormone, insulin, insulin-like growth factor-1”. Results Ghrelin mimetics, like Anamorelin consistently increased lean body mass, improved symptoms and quality of life, and have not shown an increase in tumor proliferation in CACS. There were no substantial evidence to support that growth hormone, insulin and insulin-like growth factor-1 would beneft patients with CACS. Conclusions Ghrelin mimetics and potentiation of ghrelin, represented by Anamorelin have shown positive effects in CACS, and would be applied in clinics in the near future.
2015 Vol. 2 (2): 63-67 [Abstract] ( 224 ) HTML PDF (1213 KB)  ( 198 )
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