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Advances of body composition analysis in clinical application of cancer patients |
Liu Yining ,Cui Jiuwei |
Cancer Center the First Hospital of Jilin University Changchun 130000 Jilin China |
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Abstract Body composition refers to the proportion of various body components muscle adipose tissue skeletal muscle tissue
etc. which is a symbol to measure the distribution of tissues in the body one of which can make a great difference on body health or
disease. 40%-80% of tumor patients are prone to be complicated with malnutrition and even progress to cachexia. The occurrence of
malnutrition seriously affects the survival and prognosis of tumor patients and reduces their tolerance and sensitivity to radiotherapy and
chemotherapy. During the occurrence development and treatment of tumors the relevant body composition indexes often vary with the
changes of patients' nutritional status the degree of malignancy of the disease the rate of progression and the adjustment of therapy.
Therefore human composition as an important monitoring index is related to the survival prognosis analysis and drug toxicity
evaluation of patients. Well body composition analysis is an important way to assess the nutritional status of tumor patients and predict
their quality of life early which is helpful to make individualized treatment according to the current status of patients. With the
widespread use of noninvasive body composition measurements body composition analysis has unique advantages in diagnosis and
evaluation of nutritional status of cancer patients prediction of efficacy and toxicity of anti - tumor drugs as well as survival and
prognosis. A number of clinical trials related to body composition in cancer patients have been conducted in this article we provide an
overview of the clinical application of body composition analysis in cancer patients.
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