头颈部放射性口腔黏膜炎患者营养状况与生活质量相关性研究

doi:10.16689/j.cnki.cn11-9349/r.2020.01.010

Abstract
Figure/Table
References (0)
Related Citation (15)

Download: PDF (502 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective To investigate the correlation between nutritional status and quality of life in patients with head and neck tumors with radiation-induced oral mucositis. Method A total of 80 patients with head and neck radioactivity were investigated using the General Information Questionnaire, the Quality of Life Scale for Cancer Patients (QLQ-C30), the Patient Supervisory Overall Rating Scale (PG-SGA), and the National Cancer Institute Common Toxicity Response Standard (NCI-CTCAE) Patients with oral mucositis were investigated. Result In total of 80 patients met the selection criteria, including 51 males and 29 females. The age ranged from 19 to 80 years, with an average age of (58.21±11.84) years. PG-SGA evaluation results： There were 12 cases of Grade A patients, 35 cases of Grade B patients, and 33 cases of Grade C patients. Physical function, role function, cognitive function, social function, general health and fatigue, pain, constipation, diarrhea and other symptoms were significantly correlated with nutritional status (P<0.05), emotional function, nausea There was no significant correlation between vomiting, shortness of breath, insomnia, loss of appetite, economic difficulties and nutritional status (P> 0.05). Conclusions Patients with head and neck radiation oral mucositis had malnutrition to varying degrees, and their nutritional status was positively correlated with quality of life (P <0.01). Therefore, improving the nutritional status of patients with head and neck radiation oral mucositis can greatly improve the quality of life of patients, improve clinical treatment outcomes, and provide reference basis for future nursing interventions.

Key words： Head and neck cancer Oral mucositis Nutrition Quality of life Correlation

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	1Wang Xuan
	2Qin Nan
	3Jiang Guichun

Cite this article:

1Wang Xuan,2Qin Nan,3Jiang Guichun. Correlation between nutritional status and quality of life in patients with head and neck radioactive oral mucositis[J]. Electron J Metab Nutr Cancer, 2020, 7(1): 52-56.

URL:

http://182.92.200.144/EN/10.16689/j.cnki.cn11-9349/r.2020.01.010 OR http://182.92.200.144/EN/Y2020/V7/I1/52

1.Torre LA, Bray F, Siegel RL, et al. Global cancer statistics, 2012. CA Cancer J Clin.2015；65(2)：87-108.
2.Cao DX, Wu GH, Zhang B, et al. Resting energy expenditure and body composition in patients with newly detected cancer. Clin Nutr. 2010；29(1)：72-77.
3.孙振球等. 医学统计学.北京：人民卫生出版社, 2014.
4.万崇华, 陈明清, 张灿珍, 等. 癌症患者生命质量测定量表EORTC QLQ-C30中文版评介. 实用肿瘤杂志.2005；(4)：353-355.
5.Habl G, Hatiboglu G, Edler L, et al. Ion Prostate Irradiation (IPI)-a pilot study to establish the safety and feasibility of primary hypofractionated irradiation of the prostate with protons and carbon ions in a raster scan technique. BMC Cancer. 2014；14：202.
6.王璇, 姜桂春. 食管癌术后病人居家支持性照护需求的研究进展. 护理研究. 2019；33(12)：2096-2100.
7.Orell H, Schwab U, Saarilahti K, et al. Nutritional counseling for head and neck cancer patients undergoing (Chemo) radiotherapy-a prospective randomized trial. Front Nutr.2019；6：22.
8.John AA, Naresh KC, Ranganath V, et al. Relationship between the nutritional status and antimicrobial protein levels with the periodontal condition in untreated head and neck cancer patients. J Family Med Prim Care. 2019；8(10)：3325-3333.
9.Zietarska M, Krawczyk-Lipiec J, Kraj L, et al. Chemotherapy-related toxicity, nutritional status and quality of life in precachectic oncologic patients with, or without, high protein nutritional support. A prospective, randomized study. Nutrients. 2017；9(10).
10.Britton B, McCarter K, Baker A, et al. Eating As Treatment (EAT) study protocol： a stepped-wedge, randomised controlled trial of a health behaviour change intervention provided by dietitians to improve nutrition in patients with head and neck cancer undergoing radiotherapy. BMJ Open. 2015；5(7)：e8921.
11.李群. 早期营养干预对头颈部肿瘤放疗后患者生活质量的影响. 中国药物与临床. 2019；19(3)：416-418.
12.Nitichai N, Angkatavanich J, Somlaw N, et al. Validation of the Scored Patient-Generated Subjective Global Assessment (PG-SGA) in Thai Setting and Association with Nutritional Parameters in Cancer Patients. Asian Pac J Cancer Prev.2019；20(4)：1249-1255.
13.Arends J, Bachmann P, Baracos V, et al. ESPEN guidelines on nutrition in cancer patients. Clin Nutr. 2017；36(1)：11-48.
14.余意. 系统营养干预对鼻咽癌治疗的影响. 南方医科大学. 2009.
15.Talwar B, Donnelly R, Skelly R, et al. Nutritional management in head and neck cancer： United Kingdom National Multidisciplinary Guidelines. J Laryngol Otol. 2016；130(S2)：S32-S40.
16.Yeh SA, Tang Y, Lui CC, et al. Treatment outcomes and late complications of 849 patients with nasopharyngeal carcinoma treated with radiotherapy alone. Int J Radiat Oncol Biol Phys. 2005；62(3)：672-679.
17.姜武忠, 廖遇平, 谢啸平. 鼻咽癌放疗后耳鼻及皮肤并发症的治疗.中华放射医学与防护杂志.2006；(3)：259-260.
18.尚庆娟. 头颈部癌患者生存质量现状及相关因素研究. 重庆医科大学.2008.
19.申红峰, 王小深, 欧光明, 等. 基于图像引导下头颈部肿瘤放射治疗患者摆位误差的相关性分析. 中国医学装备. 2016；13(10)：22-24.
20.Ehrsson YT, Sundberg K, Laurell G, et al. Head and neck cancer patients perceptions of quality of life and how it is affected by the disease and enteral tube feeding during treatment. Ups J Med Sci. 2015；120(4)：280-289.