益生菌联合麦芽糊精果糖肠内营养对胃癌患者术后的影响

doi:10.16689/j.cnki.cn11-9349/r.2020.01.009

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Abstract Objective To study the effects of probiotic enteral nutrition support combined with maltodextrin fructose drink on the recovery, subjective comfort and abdominal distension of patients with gastric cancer after operation. Methods 120 patients with gastric cancer who underwent elective surgery in Lianyungang hospital of Xuzhou Medical University from June 2016 to June 2019 were divided into two groups by random number table： control group and observation group, 60 cases in each group. Both groups underwent D2 radical gastrectomy for gastric cancer. After operation, both groups received SOX regimen for chemotherapy. The patients in the observation group were treated with probiotic enteral nutrition support combined with maltodextrin fructose beverage after operation. The patients in the control group received enteral nutrition support with probiotics. The treatment lasted for 2 weeks. The differences of intestinal microecology, nutritional status, subjective comfort and adverse reactions between the two groups were observed. Results After treatment, the number of Lactobacillus faecalis, Bifidobacterium, Enterococcus and Eubacterium in the two groups both increased, and the number of Lactobacillus, Bifidobacterium, Enterococcus and Eubacterium in the observation group was significantly higher than those in the control group (P<0.05). The levels of HB, HCT, TBIL, DBIL, IBIL, TP, ALB and PAB in the two groups were significantly increased (P<0.05), and the levels of HB, HCT, TP, ALB, PAB and ALT in the observation group were significantly higher than those in the control group (P<0.05), while the levels of TBIL, DBIL and IBIL were significantly lower than those in the control group (P<0.05). The subjective comfort score of the observation group was significantly lower than that of the control group, and the incidence of diarrhea, abdominal distension and vomiting of the observation group was significantly lower than control group (P<0.05). Conclusions Probiotic enteral nutrition support combined with maltodextrin fructose beverage can significantly reduce the incidence of abdominal distension, diarrhea and vomiting in patients with gastric cancer after operation. It is suggested that clinical application of probiotic enteral nutrition support combined with maltodextrin fructose beverage should be promoted.

Key words： Radical gastrectomy SOX regimen Probiotics Nutritional status Abdominal distension

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	Ma Dongbo

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Ma Dongbo. Effect of probiotic enteral nutrition support combined with maltodextrin fructose on postoperative patients with gastric cancer[J]. Electron J Metab Nutr Cancer, 2020, 7(1): 47-51.

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http://182.92.200.144/EN/10.16689/j.cnki.cn11-9349/r.2020.01.009 OR http://182.92.200.144/EN/Y2020/V7/I1/47

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