The relationship between dietary patterns and cancer and its mechanism of action
1Gu Ying ,2Yang Jing ,3Qin Liqiang
1Department of Clinical Nutrition The First Affiliated Hospital of Soochow University Suzhou 215000 Jiangsu China
2Department of
Clinical Nutrition The First Affiliated Hospital of Soochow University Suzhou 215000 Jiangsu China
3
School of Public Health
Soochow University Suzhou 215000 Jiangsu China
Abstract：As we all know diet is closely related to cancer. Healthy diet pattern can reduce the risk of some cancers while
inappropriate diet structure may be an important inducement leading to systemic metabolic diseases such as tumors. In recent years
more and more studies have explored the influence of different diet patterns on the morbidity mortality and treatment effect of tumors.
This paper combs several diet patterns that have attracted much attention at present Including the relationship between Mediterranean
diet Ketogenic diet and Pro-inflammatory diet and tumor and the possible mechanism of action. The results show that Mediterranean
diet can reduce the incidence and overall mortality of colorectal cancer prostate cancer respiratory and digestive system cancer breast
cancer oropharyngeal cancer oral cancer and throat cancer by regulating hormone levels activating antioxidant mechanism
stimulating immune system and down-regulating carcinogenic factors. Ketogenic diet mode may slow down tumor growth by targeting
glucose metabolism amino acid metabolism mitochondrial metabolism regulating gene expression regulating signal pathway and
reducing vascularization level. It plays an important role in prolonging the survival time of patients and reversing the process of tumorinduced cachexia and has gradually become an effective anti-cancer treatment. The Pro-inflammatory diet contains more inflammatory
components which may promote the occurrence and development of tumors by increasing the inflammatory level changing the state of
microflora and affecting epigenetic remodeling.
1顾 瑛,2杨 晶,3秦立强. 膳食模式与肿瘤的关系及作用机制[J]. 肿瘤代谢与营养电子杂志, 2022, 9(6): 721-726.
1Gu Ying,2Yang Jing,3Qin Liqiang. The relationship between dietary patterns and cancer and its mechanism of action. Electron J Metab Nutr Cancer, 2022, 9(6): 721-726.
