1Department of Nutrition, The Forth Hospital of Hebei Medical University, Shijiazhuang 050000, Hebei, China； 2Department of Thoracic Surgery, The First Hospital of Hebei Medical University, Shijiazhuang 050000, Hebei, China； 3Department of Nutrition, The Third Hospital of Hebei Medical University, Shijiazhuang 050000, Hebei, China；4Department of Nutrition, The First Hospital of Hebei Medical University, Shijiazhuang 050000, Hebei, China
Abstract：Tangerine peel, which was first published in the Shennongs herbal, is the dried and mature peel of the rutaceous plant orange and its cultivated varieties, also known as tangerine peel. Tangerine peel, tasting bitter and warm, returning lung, spleen main and collateral channels, have the effect of “regulating qi and strengthening spleen, dampening phlegm”. Hesperidin is one of the main active ingredients of flavonoids tangerine peel, formula for C28H34O15, structure of dihydroflavonoside, and appears as white acicular crystal. Hesperidin mainly exists in the mature peel of orange and cultivated varieties of rutaceae, and its biological activity has been widely noted. In recent years, with the in-depth study of hesperidin, many pharmacological activities have been proved and widely used in medicine, food and other scientific fields. Previous research has shown that hesperidin has anti-inflammatory, antioxidant, anti-radiation, anticancer, cardiovascular system protection, improve blood glucose, lipid metabolism, nervous system protection and other biological activities. Combining the domestic and foreign advances in hesperidin, we reviewed the latest research progress and biological efficacy of hesperidin and to forecast its future development trend.
1谢琪，2王强， 1高淑清，3雷敏，4李增宁. 橙皮苷生物活性作用及机制研究进展[J]. 肿瘤代谢与营养电子杂志, 2020, 7(1): 13-17.
1Xie Qi, 2Wang Qiang, 1Gao Shuqing, 3Lei Min, 4Li Zengning . Advances on the biological activity and mechanism of hesperidin. Electron J Metab Nutr Cancer, 2020, 7(1): 13-17.
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