1General Department Cancer Hospital of Huanxing Chaoyang District Beijing Beijing 100122 China
2Beijing AiNST Medical
Technology CO. LTD. Beijing 102206 China
3Department of General Diseases National Cancer Center/ Cancer Hospital Chinese
Academy of Medical Sciences and Peking Union Medical College Beijing 100021 China
Abstract： Objective To analyze the vitamin deficiency of hospitalized cancer patients explore the correlation between vitamin
deficiency and nutritional risk and malnutrition and provide scientific reference basis for nutritional intervention of cancer
patients. Method A total of 1257 cancer patients in our hospital from August 2021 to June 2022 were selected vitamins were
determined using Qlife Lab 9000plus liquid chromatography triple quadrupole tandem mass spectrometer to analyze the proportion of
various vitamin deficiencies. Nutritional risk screening 2002 was used for nutritional risk screening and the Global Leadership
Initiative on Malnutrition standard was used for the diagnosis of malnutrition. Analyze the correlation between nutritional risk or
malnutrition and vitamin deficiency. Result The average age of 1257 cancer patients was 59. 71 ± 11. 17 years old. There were 783
males and 474 females with an average body mass index of 23. 35 ± 3. 62 kg / m
2
. The incidence of nutritional risk was 35. 88%
NRS 2002 ≥ 3 points and the incidence of malnutrition was 22. 12% . All water - soluble vitamins are deficient with varying
degrees with vitamin B1 deficiency accounting for the most 80. 9% and vitamin B3 deficiency accounting for the least 1. 4% . Fat
soluble vitamins were deficient in vitamin D alone accounting for 89. 4%. Compared with patients without nutritional risk there was a
statistically significant difference in the proportion of vitamin A and vitamin C deficiency among patients with nutritional risk 39%
vs. 45. 5% P<0. 05 . Compared with patients without malnutrition there was a statistically significant difference in the proportion of
vitamin A and folic acid deficiency among patients with malnutrition 55. 1% vs. 47. 6% P<0. 05 . Conclusion The proportion of
vitamin D vitamin B1
folic acid and vitamin C deficiency in hospitalized cancer patients was high. The nutritional evaluation of
cancer patients should consider the vitamin levels to guide rational vitamin supplementation in clinic.
1姚克青,1代 忠,1陈 兵,2商维虎,3丛明华. 基于质谱技术的肿瘤患者维生素水平与营养状况相关性分析[J]. 肿瘤代谢与营养电子杂志, 2023, 10(4): 523-529.
1Yao Keqing,1Dai Zhong,1Chen Bing,2Shang Weihu,3Cong Minghua. Study on the correlation between vitamin deficiency and nutritional status in hospitalized cancer patients. Electron J Metab Nutr Cancer, 2023, 10(4): 523-529.
