|
|
|
| Metabonomics and its application in tumor research |
| 1 Zhang Nan, 2 Kong Dan, 1 Yang Shujia, 1 Jin Xiaoming |
| 1
Department of Pathology, School of Basic Medicine, Harbin Medical University, Harbin 150081, Heilongjiang, China；2
Department of
Gynecology, the Third Affiliated Hospital of Harbin Medical University, Harbin 150040, Heilongjiang, China |
|
|
|
|
Abstract Metabolomics is an emerging "omics" after genomics, proteomics and transcriptomics, which is often used in disease
diagnosis, medical research and development, nutrition and food science, toxicology, environmental science, botany and other fields
closely related to human health. Since the 20th century, the number of articles on metabonomics published every year has been
increasing. In particular, the research of metabonomics in tumor is also increasing. On the surface, metabonomics is developing rapidly,
but it still lags far behind genomics and proteomics. The emergence of metabonomics is the necessity of life science research.
Metabonomics is a new subject for qualitative and quantitative analysis of small molecular metabolites in a certain organism or cell.
Tumor is a common disease that seriously endangers human health and life, and all tumors are characterized by changes in cell
metabolism. Therefore, metabolomics shows great potential in the screening of tumor metabolic markers, the evaluation of prognosis,
and the design of drug targets.At present, metabonomics has been widely used in the study of various tumors, and with the continuous
progress of metabonomics analysis platform, bioinformatics technology and the establishment of database, it will play a very important
role in the clinical diagnosis and treatment of tumors. In this review, metabolomics and its research progress in tumor are reviewed.
|
|
Received: 02 October 2021
|
|
|
|
|
|
|
