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| Progress of perioperative immunonutrition therapy for gastric cancer |
| Wang Miaozhou1, Liu Yi1, Zhao Junhui1, Chai Haipin1, Lu Na1, Zhang Tao2 |
| 1.Department of Oncology, Affiliated Hospital of Qinghai University, Xining 810001, Qinghai, China；2.Department of Gastroenterology, The Second Peoples Hospital of Xining City, Xining 810003, Qinghai, Chin |
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Abstract Immunity is a physiological function to ensure human health. At present, human beings have experienced four stages in their understanding and development (empirical immunology, scientific immunology, modern immunology, applied immunology). Among them, in the application of immunology stage, derived a lot of branches, such as: immunotherapy, immune prevention and immune nutrition. With the emergence of immunotherapy in malignant tumors, it not only proves its feasibility and importance in the treatment of malignant tumors, but also makes people extend this idea to solve the problem of malnutrition in tumor patients. This method of regulating immunotherapy for malnutrition is called “immunonutrition therapy” and has been developed rapidly in clinical practice in recent years. Among them, gastric cancer has the highest incidence of malnutrition, and the development of immunonutrition therapy in gastric cancer has attracted much attention. It is hoped that this treatment can reduce perioperative adverse clinical outcomes, prolong patients overall survival, and improve patients quality of life. In this paper, the mechanism of malnutrition in patients with gastric cancer, the role of immune nutrition in maintaining intestinal barrier, and the application, mechanism and efficacy of common immunonutrients in patients with gastric cancer during perioperative period were reviewed, so as to provide clinical reference for the treatment of immune nutrition in patients with gastric cancer during perioperative period.
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