放射治疗中心恶性肿瘤患者营养状况的横断面调查研究

doi:10.16689/j.cnki.cn11－9349/r.2019.04.010

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Abstract ObjectiveTo investigate the prevalence of nutrition risk and malnutrition in cancer patients hospitalized for radiotherapy. Methods We involved 330 patients with malignant tumors who were admitted to the radiotherapy center from August to October 2017 in Chongqing University Cancer Hospital. The nutrition risk was evaluated by the nutritional risk screening 2002 （NRS 2002）,the nutritional status was assessed with the patient-generated subjective global assessment （PG-SGA） questionnaire, the Karnofsky performance status （KPS）was used to evaluate the physical status. Physical indexes and laboratory examination results were recorded within 48 hours after admission. ResultsA total of 330 patients completed the nutritional survey. There were 227 males and 103 females, accounting for 68% and 31.2%, respectively. The mean age was 54.0±11.4 years old. 28.8% of the patients had nutritional risk （score≥3）,according to the PG-SGA score, 52.7% had the malnutrition （PG-SGA score≥4）. Among different cancers, patients with nasopharyngeal cancer had the highest prevalence of nutritional risk （29.3%）, the nutritional risk was 28.1%,18.1% and 15.2%, respectively, for patients with lung cancer, oral cancer and esophageal cancer who intending to accept radiotherapy. There was a negative correlation between BMI and PG-SGA score, a positive correlation between the NRS 2002 score and the PG-SGA score. Age （≥65 years）, albumin （<40g/L）, prealbumin （<150g/L）, Karnofsky （<80） are the risk factors of nutritional risk and severe malnutrition （P<0.05）. ConclusionThe prevalence of nutritional risk in patients with radiotherapy was medium, but the prevalence of malnutrition in patients with radiotherapy was high. Nutrition management of the patients was very necessary for cancer patients receiving radiotherapy. In clinical practice, combined with the nutritional status of patients, PG-SGA score can be used as a reference standard for nutritional intervention.

Key words： Cancer Radiotherapy Nutritional risk screening 2002 Patient-generated subjective global assessment

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	Articles by authors
	FENG Chang-yan
	HUANG Qing-qing
	YU Hui-qing

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FENG Chang-yan,HUANG Qing-qing,YU Hui-qing. A cross-sectional study on nutritional risk and malnutrition of hospitalized patients with malignant tumors in radiotherapy center[J]. Electron J Metab Nutr Cancer, 2019, 6(4): 442-446.

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http://182.92.200.144/EN/10.16689/j.cnki.cn11－9349/r.2019.04.010 OR http://182.92.200.144/EN/Y2019/V6/I4/442

1.周福祥. 放疗性营养不良临床评估及治疗. 肿瘤代谢与营养电子杂志. 2014；1（2）:21-25.
2.Kondrup J, Rasmussen HH, Hamberg O, et al. Nutritional risk screening （NRS 2002）:a new method based on an analysis of controlled clinical trials. Clin Nutr. 2003；22（3）:321-336.
3.Jie B, Jiang ZM, Nolan MT, et al. Impact of preoperative nutritional support on clinical outcome in abdominal surgical patients at nutritional risk. Nutrition. 2012；28（10）:1022-1027.
4.石英英,张晓伟,袁凯涛,等. PG-SGA操作标准介绍.中华肿瘤防治杂志. 2013；20（22）:1779-1782.
5.Song C, Cao J, Zhang F, et al. Nutritional risk assessment by scored patient-generated subjective global assessment associated with demographic characteristics in 23,904 common malignant tumors patients. Nutr Cancer. 2019；71（1）:1-11.
6.杨剑,张明,蒋朱明,等. 营养筛查与营养评定:理念、临床实用及误区.中华临床营养杂志. 2017；25（1）:59-64.
7.詹斯·康卓普, 雷米·梅耶. 营养风险筛查2002改善临床结局. 中华临床营养杂志. 2013；21（3）:133-138.
8.张雪, 任紫薇, 徐鹤, 等. NRS 2002在食管癌放疗患者中的应用及营养护理. 中国继续医学教育. 2018；10（17）:159-162.
9.Usal D, Mentes B, Akmansu M, et al. Evaluation of nutritional status in cancer patients receiving radiotherapy:a prospective study. Am J Clin Oncol. 2006；29（2）:183-188.
10.Prevost V, Joubert C, Heutte N, et al. Assessment of nutritional status and quality of life in patients treated for head and neck cancer. Eur Ann Otorhinolaryngol Head Dis. 2014；131（2）:113-120.
11.Fu Z, Xu H, Song C, et al. Validity of the Chinese version of the patient-generated subjective global assessment（PG-SGA） in lung cancer patients. J Nutr Oncol. 2016；1:52-58.
12.Demirel B, Atasoy BM. Comparison of three nutritional screening tools to predict malnutrition risk and detect distinctions between tools in cancer patients receiving radiochemotherapy. Nutr Cancer. 2018；70（6）:867-873.
13.Ottery FD. Rethinking nutritional support of the cancer patient: the new field of nutritional oncology. Semin Oncol.1994；21（6）:770-778.
14.任杰, 袁志, 张欣平, 等. 头颈部肿瘤患者放疗期间营养状况与生活质量现状及二者相关性分析. 解放军医药杂志. 2018；30（7）:18-21.
15.Hebuterne X, Lemarie E, Michallet M, et al. Prevalence of malnutrition and current use of nutrition support in patients with cancer. JPEN J Parenter Enteral Nutr. 2014；38（2）:196-204.
16.Moslemi D, Nokhandani AM, Otaghsaraei MT, et al. Management of chemo/radiation-induced oral mucositis in patients with head and neck cancer:a review of the current literature. Radiother Oncol. 2016；120（1）:13-20.
17.Villa A, Sonis ST. Pharmacotherapy for the management of cancer regimen-related oral mucositis. Expert Opin Pharmacother. 2016；17（13）；1801-1807.
18.商红, 刘芬,皮玉菊. 肺癌患者放疗期间营养状况及其影响因素研究. 护理管理杂志. 2016；（6）:391-393.
19.Qiu C, Yang N, Tian G, et al. Weight loss during radiotherapy for nasopharyngeal carcinoma:a prospective study from northern China. Nutr Cancer. 2011；63（6）:873-879.
20.Saito N, Imai Y, Muto T, et al. Low body mass index as a risk factor of moderate to severe oral mucositis in oral cancer patients with radiotherapy. Support Care Cancer. 2012；20（12）:3373-3377.
21.陈文政, 张春华,王晓松, 等. 肺癌患者营养状况与放疗不良反应的相关性研究. 实用癌症杂志. 2018；33（9）:1439-1441.
22.Langlais CS, Cowan JE, Neuhaus J, et al. Obesity at diagnosis and prostate cancer prognosis and recurrence risk following primary treatment by radical prostatectomy. Cancer Epidemiol Biomarkers Prev. 2019；28（11）:1917-1925.
23.黎娜,刘洁,林欣,等. 鼻咽癌住院患者营养状况与PG-SGA评分相关性研究. 肿瘤代谢与营养电子杂志. 2019；6（2）:200-205.
24.Kido Y. The issue of nutrition in an aging society. J Nutr Sci Vitaminol （Tokyo）. 2015；61 suppl:s176-s177.
25.卓银霞, 热依娜, 李萍. 肿瘤患者营养不良的研究进展. 护理管理杂志. 2010；10:722-724.
26.刘莹, 郝晓慧, 王玉华,等. 老年肿瘤患者营养状况及护理进展. 齐鲁护理杂志. 2014；20（18）:49-50.
27.Seo SH, Kim SE, Kang YK, et al. Association of nutrition status-related indices and chemotherapy-induced adverse events in gastric cancer patients. BMC Cancer. 2016；16（1）:900.
28.Penel N, Vanseymortier M, Bonneterre ME, et al. Prognostic factors among cancer patients with good performance status screened for phase I trials. Invest New Drugs. 2008；26（1）:53-58.
29.Li G, Gao J, Liu ZG, et al. Influence of pretreatment ideal body weight percentile and albumin on prognosis of nasopharyngeal carcinoma: long-term outcomes of 512 patients from a single institution. Head Neck. 2014；36（5）:660-666.
30.Cacicedo J, Casquero F, Martinez-Indart L, et al. A prospective analysis of factors that influence weight loss in patients undergoing radiotherapy. Chin J Cancer. 2014；33（4）:204-210.
31.廖正凯, 付正明, 曹振,等. 放疗患者的营养支持. 肿瘤代谢与营养电子杂志. 2015；2（2）:23-25.
32.Castillo-Martinez L, Castro-Eguiluz D, Copca-Mendoza ET,et al. Nutritional assessment tools for the identification of malnutrition and nutritional risk associated with cancer treatment. Rev Invest Clin. 2018；70（3）:121-125.