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| Perioperative enteral nutrition on the prognosis of patients with esophageal cancer#br# |
| ZHOU Cheng-wei, XU Fen, SU Wen-min, ZHAO Xiao-dong |
| ZHOU Cheng-wei, XU Fen, SU Wen-min, ZHAO Xiao-dong |
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Abstract Objective In most cases, preoperative and postoperative fasting can aggravate the nutritional status and body immunity, and increase the incidence of infection and mortality rate of patients with alimentary tract malignant tumor. The objective of this study is to investigate the effects of perioperative enteral nutrition on the prognosis of patients with esophageal cancer after operation. Methods A prospective randomized controlled clinical study was designed. The patients with esophageal cancer who underwent operation in our hospital were randomly divided into enteral nutrition group and total parenteral nutrition group. 40 cases were carried out in EN group, and 39 cases in PN group. In EN group, enteral nutrition solution 600ml/d were added from 5 days before operation, based on normal diet, and they were given enteral nutrition within 24h after operation. In PN group, parenteral nutrition (750kcal/d) were added from 5 days before operation, based on normal diet, and were given intravenous nutrition after operation. The changes of peripheral blood lymphocyte count, serum albumin, anal exhaust recovery time and defecation recovery time, infection, anastomotic leakage and cardiovascular events were observed in the two groups. Results The average time for anal exhaust recovery and defecation recovery in EN group was shorter than PN group with statistical difference (P<0.05). Before and after operation, the lymphocyte count, serum albumin count in EN group was lower than PN group with statistical difference (P<0.05). Postoperative infection and anastomotic fistula in EN group was less than in PN group, but more cases of abdominal distension. Conclusions EN is superior to PN, and it has a positive impact on the prognosis of patients with esophageal cancer in postoperative period. It is worth promoting as an important part of fast track surgery.
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