|
|
|
| Cutting off the source of nutrients for tumor cells—the effect of low-carbohydrate ketogenic diet on tumor cell metabolism |
| Ma Yifei,Yang Nailong |
| Department of Endocrine The Affiliated Hospital of Qingdao University Qingdao 266003 Shandong China |
|
|
|
|
Abstract In recent years the influence of daily diet on tumor progression has received extensive attention with the research on the
nutrition method and metabolic pathway in tumor cells much deeper. It is generally recognized that compared with normal cells most
tumor cells are highly dependent on the aerobic glycolysis based on glucose to obtain energy whereas unable to utilize amino acids and
ketone bodies. Therefore it is proposed to cut off the nutrient source of tumor cells through restricting carbohydrate intake thus
restraining tumor cells from growing and divising. This review aims to describe the nutritional and metabolic mechanism of tumor cells
concisely and discuss about the effects low-carbohydrate ketogenic diet has on the apparence and metabolism of tumor cells from
various perspectives.
|
|
Received: 24 April 2023
|
|
|
|
|
|
|
