|
|
|
| Supplement β-hydroxy-β-methylbutyrate on muscle quality and nutritional outcome in patients with liver cirrhosis |
| 1Zuo Dan,2Huang Biao,3Zuo Bingyu,2Kuang Gang,2Hu Dabi,4Luo Chunli |
| 1Department of Clinical Nutrition Chongqing Dazu District People ' s Hospital Chongqing 402360 China
2Department of Critical
Medicine Chongqing Dazu District People ' s Hospital Chongqing 402360 China
3Xinjiang medical university Urumqi 830017
Xinjiang China School of Stomatology Xinjiang Medical University Urumqi 830017 Xinjiang China
4Department of Oncology
Chongqing Dazu District People's Hospital Chongqing 402360 China |
|
|
|
|
Abstract Objective Research β-hydroxy-β-methylbutyrate HMB on muscle quality and nutritional status of patients with liver
cirrhosis. Method The patients with cirrhosis who met the inclusion criteria were selected from August 2021 to August 2022. They were
randomly divided into control group n = 30 and test group n = 30 . Both groups were given routine treatment such as liver protection
enzyme lowering and nutritional treatment. On the basis of the treatment in the control group the experimental group was treated with
oral nutritional supplements rich in HMB . The body weight albumin grip strength skeletal muscle index SMI triceps skinfold
thickness TSF arm muscle circumference AMC liver function Child-Pugh grade and Barthel index score of the two groups were
compared at three time points 0 3 and 6 weeks . Result The body weight and SMI albumin of patients in the test group were
significantly increased and the difference between the two groups was statistically significant P<0. 05 . TSF and AMC decreased in
both groups However there was no significant difference between the two groups P>0. 05 . There was no significant difference in
Child-Pugh liver function grading and Barthel index between the two groups P>0. 05 . Conclusion Myopenia is more common in
patients with liver cirrhosis due to the damage of metabolism and synthesis. This study found that HMB nutrition can improve the
function of skeletal muscle and the nutritional status of the body to a certain extent through the intervention of liver cirrhosis patients
Inhibit the decomposition of muscle and protein increase the muscle quality of patients but do not improve the damage degree of liver
function and personal self-care ability.
|
|
Received: 30 January 2023
|
|
|
|
|
|
|
