Abstract Objective To explore the effects of enteral nutrition and parenteral nutrition on the nutritional status and complications of patients with esophageal cancer during perioperative periodMethods 73 patients with esophageal cancer during perioperative period treated in the Second People's Hospital of Huai'an from January 2017 to June 2018 were retrospectively analyzed. They were divided into 23 cases in total parenteral nutrition (TPN) group and 50 cases in total enteral nutrition (TEN) group according to different ways of nutrition intervention. The TPN group was given intravenous nutritional, and the TEN group was given enteral nutritional via a nasal feeding tube (through the nose to the beginning of the jejunum). The nutritional and immune indexes, postoperative intestinal function and safety indexes in the two groups were compared.Results There was no significant difference in the weight loss, serum albumin and lymphocyte group between the two groups of patients on admission (P>0.05). The comparison of serum albumin and lymphocyte counts in the TPN group, and the comparison of lymphocytes in the TEN group at different time points showed statistically significant differences (P<0.05). The weight loss of TEN group was lower than that of TPN group, and the difference was statistically significant；Serum albumin at 72h and 120h after the surgery in the TEN group was lower than that in the TPN group, the lymphocytes at 120h after the surgery in the TEN group were higher than that in the TPN group, and the differences were statistically significant (P<0.05)；The recovery time of anal exhaustion and bowel sounds in the TEN group were shorter than those in the TPN group, and the differences were statistically significant (P<0.05). There was no significant difference in safety between the two groups (P>0.05).Conclusion For perioperative patients with esophageal cancer, total enteral nutrition is generally better than total parenteral nutrition, but total parenteral nutrition can quickly increase serum albumin levels.
Yu Jingjing,Gu Runhuan,Li Xiaojie, et al. Effects of different nutritional approaches on the nutritional status of patients with esophageal cancer during perioperative period[J]. Electron J Metab Nutr Cancer, 2020, 7(4): 465-468.
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