改良格拉斯哥预后评分预测晚期胰腺癌预后的临床价值

doi:10.16689/j.cnki.cn11-9349/r.2020.04.012

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Abstract ObjectiveTo investigate the effect of modified Glasgow prognosis score (mGPS) on the survival of patients with advanced pancreatic cancer, and to evaluate its potential clinical value in the prognosis of advanced pancreatic cancer. MethodsThe clinical data of 56 patients with advanced pancreatic cancer treated in the Department of oncology and gastroenterology, the First Affiliated Hospital of Nanjing Medical University from January 2015 to December 2018 were retrospectively analyzed. The relationship between mGPS, clinical features and prognosis was analyzed. Kaplan Meier method was used to draw survival curve, log-rank was used for univariate analysis, and Cox proportional hazard model was used for multivariate analysis to analyze the prognostic factors affecting poor prognosis of patients with advanced pancreatic cancer. Results Among the 56 patients, 32 were male and 24 were female. There were 29, 21 and 6 patients with mGPS score of 0, 1 and 2 respectively. Univariate analysis showed that age ≥ 65 years (P=0.035), high mGPS score (P<0.001) and no chemotherapy (P<0.001) were risk factors for OS in patients with advanced pancreatic cancer. Further multivariate Cox regression analysis showed that age ≥ 65 years (P=0.021), mGPS score of 2 (P<0.001) and non chemotherapy (P<0.001) were independent poor prognostic factors of advanced pancreatic cancer. Conclusion mGPS has important clinical significance in evaluating the prognosis of patients with advanced pancreatic cancer. High mGPS score indicates poor prognosis.

Key words： Pancreatic cancer Modified Glasgow prognostic score Treatment outcome Prognosis

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	Articles by authors
	Liu Yiqian
	Wang Jian
	Liu Lingxiang
	Shu Yongqian

Cite this article:

Liu Yiqian,Wang Jian,Liu Lingxiang, et al. The clinical value of modified Glasgow prognosis score in predicting the prognosis of advanced pancreatic cancer[J]. Electron J Metab Nutr Cancer, 2020, 7(4): 438-442.

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http://182.92.200.144/EN/10.16689/j.cnki.cn11-9349/r.2020.04.012 OR http://182.92.200.144/EN/Y2020/V7/I4/438

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