Abstract The incidence of malignant bowel obstruction (MBO) in advanced tumors is about 5%-43%. The routine treatment methods of MBO include operation, medicine, nutrition therapy, gastrointestinal decompression, stent placement and traditional Chinese medicine. Due to the presence of digestive tract obstruction, most MBO patients are unable to eat or can only eat a small amount of food. As long as the gut is functioning, try to use enteral nutrition.The basic principle for the treatment of malnutrition should be to meet the patients energy needs“protein needs” fluid requirements and micronutrient requirements. Early nutritional therapy is very important for improving the quality of life and prolonging the survival period. Partial enteral nutrition (PEN)+ partial parenteral nutrition (PPN) or total parenteral nutrition (TPN) were mainly used for nutritional treatment. The types of enteral nutrition preparations and parenteral nutrition preparations that can be used by MBO patients were described in this paper.
1.HSU J, SEVAK S.Management of malignant large-bowel obstruction［J］.Diseases of the Colon & Rectum, 2019, 62(9):1028-1030.
2.LEGENDRE H, Vanhuyse F, Caroli-Bosc F X, et al. Survival and quality of life after palliative surgery for neoplastic gastrointestinal obstruction［J］. Eur J Surg Oncol, 2001, 27(4):364-367.
3.BERGER J, LESTER P, RODRIGUES L. Medical therapy of malignant bowel obstruction with octreotide, dexamethasone, and metoclopramide［J］.Am J Hosp Palliat Care, 2016, 33(4):407-410.
4.石汉平, 许红霞等.营养不良的五阶梯治疗［J］.肿瘤代谢与营养电子杂志, 2015, 2(1):29-33.
5.中国抗癌协会.肿瘤营养治疗通则［J］.肿瘤代谢与营养电子杂志, 2016, 3(1):34-39.
6.中华医学会肠外肠内营养学分会.肿瘤患者营养支持指南［J］.中华外科杂志, 2017, 55(11):801-829.
7.蒋朱明, 于康.为什么要研讨肠内营养制剂的分类［J］.临床外科杂志, 2004, 12(5):263-264.
8.LUBOS S.临床营养基础［M］.上海: 复旦大学出版社, 2007:230-240.
9.MAGNUSON B L, CLIFFORD T M, HOSKINS L A, et al. Enteral nutrition and drug administration,interactions,and complications［J］.Nutr Clin Pract, 2005, 20(6):618-624.
10.ARENDS J, BACHMANN P, BARACOS V, et al.ESPEN guidelines on nutrition in cancer patients［J］. Clin Nutr, 2017, 36(1):11-48.
11.Singer P, Blaser A R, Berger M M, et al.ESPEN guideline on clinical nutrition in the intensive care unit［J］.Clin Nutr, 2019, 38(1):48-79.
12.GOMES F, SCHUETZ P, BOUNOURE L, et al.ESPEN guidelines on nutritional support for polymorbid internal medicine patients ［J］.Clin Nutr, 2018, 37(1):336-353.
13.YAN S, LI M, YANG D, et al.Associations between omega-3 fatty acid supplementation and anti-inflammatory effects in patients with digestive system cancer: A meta-analysis［J］.Nutr Cancer, 2020, 72(7):1098-1114.
14.ARENDS J, BACHMANN P, BARACOS V, et al.ESPEN guidelines on nutrition in cancer patients ［J］.Clin Nutr, 2017, 36(1):11-48.
15.McCLAVE S A, DIBAISE J K, MULLIN G E, et al.ACG clinical guideline: Nutrition therapy in the adult hospitalized patient［J］.Am J Gastroenterol, 2016, 111(3):315-334.
16.WEIMAIM A, BRAGA M, CARLI F, et al.ESPEN guideline: Clinical nutrition in surgery［J］.Clin Nutr, 2017, 36(3):623-650.
17.BOZZETTI F.The role of parenteral nutrition in patients with malignant bowel obstruction［J］.Support Care Cancer, 2019, 27(12):4393-4399.
18.CHOUHAN J, GUPTA R, ENSOR J, et al. Retrospective analysis of systemic chemotherapy and total parenteral nutrition for the treatment of malignant small bowel obstruction［J］.Cancer Med, 2016, 5(2):239-247.
19.HASENBERG T, ESSENBREIS M, HEROLD A, et al.Retracted: Early supplementation of parenteral nutrition is capable of improving quality of life,chemotherapy-related toxicity and body composition in patients with advanced colorectal carcinoma undergoing palliative treatment: Results from a prospective,randomized clinical trial［J］.Colorectal Disease, 2010, 12(10Online):e190-e199.
20.SHANG E, WEISS C, POST S, et al.Retraction: The influence of early supplementation of parenteral nutrition on quality of life and body composition in patients with advanced cancer［J］.JPEN J Parenter Enteral Nutr, 2006, 30(3):222-230.
21.CADENA AJ, HABIB S, RINCON F,et al.The benefits of parenteral nutrition (pn) versus enteral nutrition (en) among adult critically ill patients: What is the evidence? A literature review［J］.J Intensive Care Med, 2020, 35(7):615-626.
22.NEJATINAMINI S, KUBRAK C, LVAREZ-CAMACHO M, et al. Head and neck cancer patients do not meet recommended intakes of micronutrients without consuming fortified products［J］.Nutr Cancer, 2018, 70(3):474-482.
