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| Principles in cancer nutrition therapy |
| 1Wang Lin ，2Cong Minghua ，3Cui Jiuwei ，4Xu Hongxia ，5Chen Junqiang ，6Li Tao ，7Li Zengning ，8Liu Ming ，3Li Wei ，9GuoZengqing ，10Song Chunhua ，11Weng Min ，12Zhang Qi ，2Zhang Xi ，2Tang Meng ，3Liang Tingting ，13Chen Xiaofeng ，13Liu Lingxiang ，14Zhang Feng ，1Jia Pingping ，1Yu Kaiying ，15Tang Xiaoli， 16Chen Yongyi ，17Lu Qian ，18Zhou Fuxiang ，19Fu Zhenming ，1Yang Liuqing ，1Huang Huiling ，1Wang Xiaolin ，1Shi Hanping |
| 1Department of Gastrointestinal Surgery / Clinical Nutrition Beijing Shijitan Hospital Capital Medical University Key Laboratory of
Cancer FSMP for State Market Regulation Beijing 100038 China
2Department of Comprehensive Oncology National Cancer Center /
National Clinical Research Center for Cancer / Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical
College Beijing 100021 China
3Cancer Center the First Hospital of Jilin University Changchun 130021 Jilin China
4Department of
Clinical Nutrition Daping Hospital Army Medical University Third Military Medical University Chongqing 400042
China
5Department of Gastrointestinal and Gland Surgery the First Affiliated Hospital of Guangxi Medical University Nanning 530021
Guangxi China
6Department of Radiotherapy Sichuan Cancer Hospital & Institute School of Medicine University of Electronic Science
and Technology of China Chengdu 610041 Sichuan China
7Department of Nutrition The First Hospital of Hebei Medical University
Hebei Province Key Laboratory of Nutrition and Health Shijiazhuang 050031 Hebei China
8Department of General Surgery the
Second Affiliated Hospital of Harbin Medical University Harbin 150001 Heilongjiang China
9
The Department of Clinical Nutrition
Clinical Oncology School of Fujian Medical University Fujian Cancer Hospital Fuzhou 350014 Fujian China
10Department of Epidemiology College of Public Health Zhengzhou University Zhengzhou 450052 Henan China
11Department of Clinical Nutrition
First Affiliated Hospital of Kunming Medical University Kunming 650032 Yunnan China
12Department of Colorectal Surgery
Zhejiang Cancer Hospital Hangzhou 310005 Zhejiang China
13Department of Oncology The First Affiliated Hospital of Nanjing
Medical University Jiangsu Province Hospital Nanjing 210029 Jiangsu China
14Department of Clinical Nutrition Affiliated Hospital
of Jiangnan University Wuxi 214122 JiangSu China
15General Medical Division Ward A Sichuan Cancer Hospital Chengdu 610041
Sichuan China
16Dean's Office Cancer Hospital Affiliated to Xiangya Medical College Changsha 410031 Hunan China
17Division of
Medical and Surgical Nursing School of Nursing Peking University Beijing 100191 China
18Department of Radiation and Medical
Oncology Zhongnan Hospital Wuhan University Wuhan 430071 Hubei China
19Cancer Center Renmin Hospital of Wuhan
University Wuhan 430060 Hubei China |
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Abstract Cancer nutrition therapy can significantly improve clinical outcomes prolong survival time improve quality of life and
save medical costs. It should be used as the first - line and basic treatment for cancer patients throughout the whole process of
treatment. The cancer patients should start the nutrition therapy entirely and actively at an early stage. According to the nutritional
diagnosis nutrition therapy should be implemented correspondingly following the four priority principles of dietary priority oral
priority nutritional education priority and enteral nutrition priority and the five - step nutrition therapy specification of nutritional
education oral nutritional supplements ONS tube feeding partial parenteral nutrition PPN and total parenteral nutrition TPN .
The basic requirement of cancer nutrition therapy is to meet the energy and nutrient requirements of cancer patients and the highest
goal is to regulate metabolism control cancer maintain body functions improve quality of life and extend survival time. The total
energy requirement is assessed using 20-25 kcal / kg·d for bedridden patients and 25-30 kcal / kg·d for active patients and the
protein supply is assessed using 1. 2-1. 5 g / kg·d . The energy supply ratio of glucose and fatty acid should be adjusted in the light
of the insulin resistance of patients. It is suggested that tumor-bearing patients should reduce the proportion of glucose and increase
fatty acid. The combination of multiple pharmacological nutrients has a positive effect on cancer patients. Nutrition therapy for endstage cancer patients requires individualization and full respect for the opinions of patients and their families.
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