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| The effect of individualized nutrition with dietary energy on postoperative radiotherapy patients with thyroid cancer |
| 1Zhou Yingjun, 1Yin Hongtao, 1Cai Lili, 2Zhou Yanqing, 3Wu Di |
| 1Department of Coronary Care Unit, Qinhuangdao First Hospital, Qinhuangdao 066300, Hebei, China; 2Operation Room, Qinhuangdao
First Hospital, Qinhuangdao 066300, Hebei, China; 3Department of General Surgery, Qinhuangdao First Hospital, Qinhuangdao
066300, Hebei, China |
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Abstract Objective To explore the effect of individualized nutritional intervention based on dietary energy on the radiotherapy
tolerance, nutritional status and quality of life of patients with postoperative radiotherapy for thyroid cancer. Method 98 patients with
postoperative radiotherapy for thyroid cancer treated in Qinhuangdao First Hospital from January 2018 to June 2020 were selected as
the research objects. According to the filing order of admission, patients were divided into control group and observation group, 49 patients
each. From radiotherapy, the control group was given routine nutrition intervention, and the observation group was given individualized
nutrition intervention based on dietary energy supply for 4 weeks. The body mass, upper arm muscle circumference and skinfold thickness,
radiation tolerance, nutritional status [serum albumin (SA), prealbumin (PA), transferrin (TF)] before and after intervention, cancer⁃related
fatigue, quality of life (FLIC) and nutritional diet compliance were compared between the two groups. Result After the intervention, the
body weight, upper arm muscle circumference and skinfold thickness of the observation group were higher than those of the control group
(P<0.05); after the intervention, the observation group had PA (350.47±52.32) mg/L, SA (35.48±2.01) g/L, TF (2.26±0.54) g/L are higher
than the control group (321.48±42.32) mg/L, (31.12±2.86) g/L, (1.90±0.50) g/L (P<0.05); the radiotherapy tolerance of the observation
group was higher than that of the control group (P<0.05); the degree of cancer⁃related fatigue in the observation group (no fatigue or mild
fatigue 48.98%, moderate fatigue 30.61%, severe fatigue 20.41%) was low In the control group (26.53%, 36.73%, 36.73%) (P<0.05);
the FLIC score of the observation group after intervention was higher than that of the control group (P<0.05); the nutrition diet compliance
of the observation group was higher than that of the control group (P<0.05). Conclusion Individualized nutritional intervention based
on dietary energy can help improve the nutritional status of patients undergoing radiotherapy for thyroid cancer, maintain their body mass,
reduce cancer⁃related fatigue, enhance radiotherapy tolerance, and improve the quality of life.
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Received: 05 July 2021
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