Abstract Objective To investigate the effects of enteral nutrition on weight, nutritional status, adverse reactions, anxiety,
sleep quality and doctor⁃patient satisfaction in patients with rectal cancer undergoing concurrent chemoradiotherapy. Methods
Patients with rectal cancer receiving chemoradiotherapy were randomly divided into study group (chemoradiotherapy combined
with enteral nutrition group) and control group (chemoradiotherapy group). Secondary study endpoints included comparison of
adverse reactions and treatment completion rates, comparison of patients′ anxiety level, sleep quality, and doctor⁃patient
relationship satisfaction, using 2 and t tests. Results From March 2019 to March 2020, 42 patients were included from Chengdu
Seventh People′s Hospital in the study group and the control group.The weight loss of the study group was significantly lower
than that of the control group(P<0.05). The decrease of hemoglobin, lymphocyte count, serum albumin and serum prealbumin in
the study group was lower than that in the control group (P<0.05).The incidence of ≥Ⅲ° bone marrow suppression and anxiety in
the study group were significantly lower than those in the control group, and the quality of sleep and satisfaction of
doctor⁃patient relationship in the study group were significantly higher than those in the control group (P<0.05).There was no
significant difference in the incidence of ≥Ⅱ° radioactive proctitis (P>0.05). Conclusion Enteral nutrition can help maintain the
weight of patients with rectal cancer after concurrent chemorradiotherapy and chemotherapy, improve the nutritional status,
reduce the incidence of bone marrow suppression, improve patients′ sleep quality and doctor⁃patient relationship satisfaction, and
reduce patients′ anxiety, which is worthy of clinical promotion.
Qing Xiaoyan,Zhu Li,Liu Dingyi, et al. Clinical study on the effect of enteral nutrition on nutritional status of patients with rectal cancer undergoing concurrent
chemoradiotherapy[J]. Electron J Metab Nutr Cancer, 2021, 8(5): 514-518.
