Abstract Abstract: Objective To compare the clinical effect of post-pyloric feeding and gastric feeding in critically ill cancer patients and seek safe and effective way of nutrition and catheterization for critically ill patients. Methods The critically ill patients, needing to receive enteral nutrition,were randomly divided into post-pyloric feeding group and gastric feeding group, stomach tube was operated by a nurse following the routine, and the post-pyloric feeding tube was done by trained physicians or nurses. Results 54 cases of critically ill cancer patients were included in the study, 28 cases were in post-pyloric feeding group, 26 cases were in gastric feeding group. Success rate of catheterization in post-pyloric feeding group was 70%, average time of catheterization was 26.96 ± 9.86 minutes. The baseline data (age structure, sex ratio, APCHE II score) of two groups had no statistical difference. Time to reach target feeds in days was shorter in post-pyloric feeding group compared to gastric feeding group (5.39±1.65 vs 7.40±2.88, P<0.05). Incidence of aspiration was lower in post-pyloric feeding group compared to gastric feeding group (3.6% vs 23.6%, P=0.03). Intensive care unit length of stay has no significant difference between the two groups (P>0.05). Incidence of pipeline blockage was higher in post-pyloric feeding group compared to gastric feeding group (32.1% vs 7.7%, P=0.026). Conclusions Post-pyloric feeding for critically ill patients can help to improve tolerance of enteral nutrition and reduce the incidence of aspiration; CORFLO feeding tube is convenient and efficient.
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