恶性肠梗阻患者的代谢紊乱

doi:10.16689/j.cnki.cn11-9349/r.2020.03.004

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Abstract Malignant bowel obstruction is malignant tumor associated intestinal obstruction common in patients with advanced ovarian cancer or gastrointestinal cancer. It’s one of the most lethal complications caused by tumor compression, tumor cell infiltration of autonomic nerves, paraneoplastic syndrome, or drug related factors. In this review, we delineate the current studies on metabolic disorders and mechanisms of malignant bowel obstruction at home and abroad and draw the following conclusions. Malignant bowel obstruction not only causes metabolic disorders of macronutrients such as glucose, protein, and fatty acids, but also causes micronutrients disorders. Intestinal dysfunction, inflammation and intestinal flora disorders, and lack of effective nutrition support contribute to the occurrence of malignant bowel obstruction. Metabolic disorders could aggravate obstruction and closely related to the prognosis. Clinical decision-making should pay attention to the metabolic situation. Recognizing the significant influence on the prognosis of patients, doctors should take active treatment to the metabolic disorder and improve quality of life.

Key words： Malignant bowel obstruction｜Macronutrients metabolic disorders｜Micronutrients metabolic disorders｜Inflammation｜Intestinal flora disorders Nutritional support

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	Luo Guijuan
	Miao Mingyong

Cite this article:

Luo Guijuan,Miao Mingyong. Metabolic disorder in MBO[J]. Electron J Metab Nutr Cancer, 2020, 7(3): 267-271.

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http://182.92.200.144/EN/10.16689/j.cnki.cn11-9349/r.2020.03.004 OR http://182.92.200.144/EN/Y2020/V7/I3/267

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