营养不良与肿瘤转移的关系及潜在机制

doi:10.16689/j.cnki.cn11-9349/r.2020.02.020

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Abstract The incidence of malnutrition in cancer patients is very high. Malnutrition will reduce the clinical efficacy，survival rate， and affect the quality of life of patients. Malnutrition and tumor metastasis interact and promote each other， which are the higher the incidence of malnutrition， the higher the rate of tumor infiltration and metastasis， the more severe the degree of malnutrition infiltration and metastasis. At the same time， with the metastasis of tumors， the incidence of malnutrition in patients also increases， ultimately， increasing the mortality rate of patients. The underlying cause of malnutrition in cancer patients is reduced nutrient intake and increased consumption. Various complications caused by the tumor itself， metabolic disorders caused by the tumor， various inflammatory factors secreted by the tumor cells， various adverse reactions and surgical complications during the treatment， and psychological factors of anxiety and depression of patients are all related to malnutrition. Malnutrition promotes tumor metastasis， and its specific mechanism may be related to the impaired immune function， inflammatory response， decreased leptin level， angiopoietin-like protein， autophagy of tumor cells， and so on. The treatment of malnutrition in patients can reduce the risk of tumor metastasis and prevent tumor metastasis can improve the nutritional status of patients. The study of the mechanisms related to malnutrition and infiltration and metastasis in cancer patients can provide a new direction for tumor treatment.

Key words： Tumor Metastasis Malnutrition

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	Articles by authors
	Liu Qian1
	Yin Zhenyu1
	Qu Caihao
	Li Xuemei
	Li Xiaomei
	Qi Wenbo
	Liu Le
	Bai Yuping
	Chen Hao

Cite this article:

Liu Qian1,Yin Zhenyu1,Qu Caihao, et al. Relationships between malnutrition and tumor metastasis and potential mechanisms[J]. Electron J Metab Nutr Cancer, 2020, 7(2): 240-244.

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http://182.92.200.144/EN/10.16689/j.cnki.cn11-9349/r.2020.02.020 OR http://182.92.200.144/EN/Y2020/V7/I2/240

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