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Abstract Although the pathogenesis of CVD is very complicated and involves a variety of risk factors， it has been generally recognized and accepted in the literature that atherosclerosis is an inflammatory disease characterized by elevated oxidative stress. Sufficient basic research and preliminary clinical studies show that atherosclerosis is potentially reversible. Based on the review and analysis of decades of research， we propose a new theory of atherosclerosis development. Due to the continued and usually worsening presence of the increased oxidative stress， vitamin C deficiency， collagen synthesis deficiency and other pathogenic factors， this abnormal mechanism of arterial wall repair will not stop， which eventually leads to the formation of atherosclerosis plaque， resulting in arterial stenosis， occlusion and myocardial ischemia. Low carbohydrate diet promotes health， optimal and personalized nutrition and plays a leading role in the treatment and prevention of coronary atherosclerosis. In this paper， the mechanism of coronary heart disease is not limited to coronary heart disease due to the depletion of antioxidants (especially vitamin C) caused by the increase of oxidative pressure caused by toxin increase. This phenomenon can also be seen in osteoporosis. The dynamic changes among oxidative stress， antioxidants (vitamin C)， and collagen synthesis were regional.
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