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| Enteral immunonutrition in elderly patients with total gastrectomy improves nutritional status and immunoloregulation |
| WEI Wei, WEN Xu, LI Gang, GU Rong-min, MING Xue-zhi, CHEN Huan-qiu, ZHOU Bin |
| Department of General Surgery, The Affiliated Cancer Hospital of Nanjing Medical University/Jiangsu Cancer Hospital, Nanjing 210009, China |
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Abstract Objective To investigate the effects of enteral immunonutrition on recovery, nutritional status, immune function in elderly gastric cancer patients after total gastrectomy. Methods 68 cases of elderly gastric cancer patients postgastrectomy were randomly divided into total PN group, EN+PN group. PN group stopped PN after taking semifluid diet. EN+PN group were tube feeding 250ml saline at the first day, 400ml PN at the second day and stopped PN after increasing to 800~1200ml at the 4th day. The recovery, serum marker on nutritional status and immune function were evaluated and compared before operation and on the 1st, 7th day after operation. Results The levels of serum total protein, albumin, prealbumin were significantly decreased in 2 groups on the 1st day after operation (P<0.05), and they were significantly increasedin EN+PN group on the 7th days after operation (P<0.05). The levels of serum IgG, IgM, the helper cells (CD8+, CD4+) and ratio of CD4+, CD8+, (CD4+/CD8+) were significantly decreased in 2 groups on the 1st day (P<0.05) after operation, and IgG, IgM, CD8+, CD4+and CD4+/CD8+ were significantly increased in EN+PN group (P<0.05) on the 7th day after operation. There were no significant difference in postoperative complication between 2 groups (P>0.05). Conclusions Postoperative early usage of enteral immunonutrition can improve the nutritional status and enhance immunity in elderly gastric cancer patients.
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| Cite this article: |
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WEI Wei,WEN Xu,LI Gang, et al. Enteral immunonutrition in elderly patients with total gastrectomy improves nutritional status and immunoloregulation[J]. Electronic Journal of Metabolism and Nutrition of, 2017, 4(2): 204-207.
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| URL: |
| http://www.ejmnc.org/EN/ OR http://www.ejmnc.org/EN/Y2017/V4/I2/204 |
| [1] |
Zhu Mingwei， Liu Chengyu. Medical nutritional therapy for patients with liver cancer[J]. Electronic Journal of Metabolism and Nutrition of, 2020, 7(2): 155-159. |
| [2] |
1ZHANG Hai-jing, 2SHENG Wei-xuan,1LIU Jin-xia,2GUAN Lei . Study on the clinical effect of Reyanbao on local pain caused by intravenous infusion drugs[J]. Electronic Journal of Metabolism and Nutrition of, 2019, 6(4): 477-481. |
| [3] |
1FAN Yue-ping， 2ZHANG Tian， 2QU Qian-nuo， 3SHI Han-ping. Interpretation of expert consensus for nutritional therapy pathway of malignant tumor in China—peripheral venous catheterization[J]. Electronic Journal of Metabolism and Nutrition of, 2019, 6(3): 301-304. |
| [4] |
GAO Chun， LI Meng， WEI Jun-min， LI Yu-zhen， TIAN Wei-jun， JIANG Hai-ping， SHEN Wei， XU Ai-guo， YU Zhen， CHEN Dong-sheng， CHEN Lian-zhen， GUAN Wen-xian， JIANG Hua， LI Da-kui， MEI Dan， YU Ji-ren， ZHAO C. Expert consensus on clinical use of compound amino acid injection[J]. Electronic Journal of Metabolism and Nutrition of, 2019, 6(2): 183-189. |
| [5] |
ZHANG Qing, LIU Xiao-yu, LI Jing, CHEN Jun . Postoperative application of “all in one” parenteral nutrition solution in patients with rectal cancer[J]. Electronic Journal of Metabolism and Nutrition of, 2018, 5(3): 269-273. |
| [6] |
. Enteral nutrition support on nutritional status in gastrointestinal cancer patients[J]. Electronic Journal of Metabolism and Nutrition of, 2018, 5(2): 198-201. |
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