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| Perioperative use of Shengmaiyin oral solution to promote rapid recovery in tumor patients after neoadjuvant chemotherapy
a randomized controlled clinical study |
| 1Yan Wenlong,1Wang Tingyun,2Liu Yi,3Liu Guokai,4Dong Xichen,1Ding Chao |
| 1Department of Anesthesiology National Cancer Center/ National Clinical Research Center for Cancer / Cancer Hospital Chinese Academy
of Medical Sciences and Peking Union Medical College Beijing 100021 China
2Department of Anesthesiology Shanxi Cancer Hospital
Taiyuan Shanxi 030013 China
3Dongzhimen Hospital Beijing University of Chinese Medicine Beijing 100007 China
4Guang'anmen
Hospital China Academy of Chinese Medical Sciences Beijing 100053 China |
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Abstract Objective To evaluate the safety and efficacy of Shengmaiyin oral solution in promoting rapid recovery during the
perioperative period in cancer patients and to explore its clinical value in enhanced recovery after surgery . Method From May 2023 to
May 2024 400 cancer patients who underwent neoadjuvant chemotherapy were recruited from the Cancer Hospital of the Chinese
Academy of Medical Sciences Shanxi Cancer Hospital Dongzhimen Hospital of Beijing University of Chinese Medicine and Guang'
anmen Hospital of the China Academy of Chinese Medical Sciences. The patients were randomly divided into two groups. The
experimental group received Shengmaiyin oral solution during the perioperative period on top of routine postoperative treatment. Primary
outcomes included quality of life QOL scores on postoperative days 1 7 and 14. Secondary outcomes included the time to first
flatus time to first defecation drainage tube removal time and length of hospital stay. Result The QOL scores on postoperative days
1 7 and 14 were significantly higher in the experimental group than in the control group P<0. 05 . The time to first flatus and first
defecation in the experimental group was earlier than in the control group with statistically significant differences P<0. 05 . There
was no statistically significant difference between the two groups in terms of drainage tube removal time and length of hospital stay P>
0. 05 . The incidence of adverse events was not significantly different between the two groups P>0. 05 . Conclusion Shengmaiyin oral
solution combined with standard care can promote rapid recovery during the perioperative period in cancer patients undergoing
neoadjuvant chemotherapy demonstrating good safety and efficacy.
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| Cite this article: |
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1Yan Wenlong,1Wang Tingyun,2Liu Yi, et al. Perioperative use of Shengmaiyin oral solution to promote rapid recovery in tumor patients after neoadjuvant chemotherapy
a randomized controlled clinical study[J]. Electron J Metab Nutr Cancer, 2025, 12(5): 643-650.
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| URL: |
| http://www.ejmnc.com//EN/ OR http://www.ejmnc.com//EN/Y2025/V12/I5/643 |
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