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| The application prospects of sheep milk in cancer treatment |
| 1Hao Zhenbo,2Bian Chao,1Li Zhijun,3Su Xiaohu |
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Inner Mongolia Medical University Inner Mongolia Clinical Medical College Hohhot 010000 Inner Mongolia China
2Department of
Radiotherapy Inner Mongolia People's Hospital Hohhot 010000 Inner Mongolia China
3College of Life Sciences Inner Mongolia
University Hohhot 010000 Inner Mongolia China |
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Abstract With the rising global incidence of cancer the importance of nutritional support in cancer treatment has become
increasingly prominent. Sheep milk rich in lactoferrin conjugated linoleic acid medium-chain fatty acids and various bioactive
peptides demonstrates significant antioxidant anti-inflammatory and immunoregulatory effects showing potential in cancer therapy.
Studies have shown that sheep milk slows tumor progression and alleviates treatment side effects through multiple mechanisms
including inducing tumor cell apoptosis inhibiting cancer cell proliferation modulating gut microbiota and improving nutritional
status. Extracellular vesicles and bioactive peptides derived from sheep milk also show new prospects in cancer drug delivery and
photothermal therapy providing a potential pathway for precise cancer treatment. Some studies have also found that sheep milk may
offer protective effects against complications arising during cancer therapy such as treatment - related anemia liver injury and
cognitive dysfunction particularly by improving intestinal function and regulating oxidative stress. Although most studies focus on cell
and animal experiments clinical research remains limited and the mechanisms of sheep milk 's complex components need further
investigation. Future research should focus on clinical validation standardization of extraction processes and multi-omics analysis to
provide theoretical support for the application of sheep milk in cancer treatment.
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