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| Effects of dietary anti-inflammatory index based nutritional support on immune function inflammatory factors cancerrelated fatigue and chemotherapy toxicity in lung cancer patients receiving chemotherapy |
| An Zhen, Wang Yan, Lei Jie, Gao Pei, Xiao Yu, Ma Jin |
| Department of Thoracic Surgery Tangdu Hospital Xi'an 710038 Shaanxi China |
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Abstract Objective To investigate the effects of dietary anti - inflammatory index on immune function inflammatory factors
cancer-related fatigue and chemotherapy toxicity in lung cancer patients receiving chemotherapy. Method A total of 133 lung cancer
patients who received chemotherapy in Tangdu Hospital of Air Force Military Medical University from February 2020 to December 2023
were selected as the study objects. According to different selection times 66 lung cancer patients who received conventional diet
management from February 2020 to December 2021 were set as the control group. A total of 67 patients with lung cancer who received
nutritional support based on dietary anti-inflammatory index from January 2022 to December 2023 were selected as the experimental
group. The nutritional status immune function cancer fatigue and inflammatory factors before chemotherapy were compared and the
toxic and side effects during chemotherapy were observed. Result At T1
T2
and T3
TP ALB PA CD4
+
CD8
+
CD4
+
/ CD8
+
in
observation group were higher than those in control group while hs-CRP and IL-6 were lower than those in control group P<0. 05 .
At T3
time point the scores of physical fatigue emotional fatigue and cognitive fatigue in the Cancer Fatigue Scale CFS of the
experimental group were lower than those of the control group P<0. 05 . The incidence of leukopenia thrombocytopenia nausea
vomiting and diarrhea in observation group were lower than those in control group P<0. 05 . Conclusion Nutritional support based on
dietary anti-inflammatory index can improve the nutritional status immune function and reduce cancer fatigue in lung cancer patients
treated with chemotherapy which has a positive effect on improving the chemotherapy effect.
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| Cite this article: |
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An Zhen,Wang Yan,Lei Jie, et al. Effects of dietary anti-inflammatory index based nutritional support on immune function inflammatory factors cancerrelated fatigue and chemotherapy toxicity in lung cancer patients receiving chemotherapy[J]. Electron J Metab Nutr Cancer, 2024, 11(5): 714-719.
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| URL: |
| http://www.ejmnc.com//EN/ OR http://www.ejmnc.com//EN/Y2024/V11/I5/714 |
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