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| Progress in the study of sarcopenia in patients with gynecologic malignancies |
| 1Yin Haining,1Zha Yingjuan,1Ding Bo,2Zhu Di,1Shen Yang |
| 1 Department of Gynecology Zhongda Hospital Southeast University Nanjing 210009 Jiangsu China
2 Department of Rheumatology
and Immunology Drum Tower Hospital Nanjing University School of Medicine Nanjing 210009 Jiangsu China |
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Abstract Sarcopenia is a syndrome closely associated with decreased muscle mass and strength as well as decreased physical
strength. As gynecologic malignancy surgery often requires extensive multi-organ surgical treatment which may also be accompanied
by long-term radiotherapy and immunotherapy leading to a higher incidence of sarcopenia in gynecologic malignancy patients which
seriously affects patients' somatic function treatment outcome and quality of life. At the same time there is increasing evidence that
sarcopenia shortens progression - free survival increases toxic side effects of chemotherapy and the incidence of postoperative
complications in patients with gynecologic malignancies. This article reviews sarcopenia in patients with gynecologic malignancies
summarizing screening and assessment methods influencing factors and nonpharmacological interventions respectively with the aim
of helping clinical staff to better understand sarcopenia in patients with gynecologic malignancies and providing a reference for the
development of targeted sarcopenia management strategies.
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