1Department of Oral and Maxillofacial Surgery Stomatological Hospital Hebei Medical University Shijiazhuang 050001 Hebei
China
2Department of Prosthodontics Stomatological Hospital Hebei Medical University Shijiazhuang 050001 Hebei China
3Department of Internal Medicine Zhangjiakou Pulmonary Hospital Zhangjiakou 075001 Hebei China
Abstract Objective To explore the relationship between the oxidative balance score OBS and periodontitis. Method A
retrospective analysis of clinical data from 5980 participants in the National Health and Nutrition Examination Survey NHANES
database from 2009 to 2012 was conducted. We described the nonlinear relationship between OBS and the risk of periodontitis using
restricted cubic splines. Logistic regression analysis was used to further describe the association between OBS and its components with
the risk of periodontitis. Subgroup and interaction analyses were employed to explore this relationship across different groups. Result
The study included 5980 patients with an average age of 51. 91 ± 14. 19 years. Of these 3301 participants had periodontitis.
Compared to participants with a low OBS those with a high OBS had a reduced risk of periodontitis OR = 0. 80 95% CI =
0. 68-0. 93 . In patients with cancer this relationship was more pronounced OR = 0. 66 95% CI = 0. 48- 0. 89 . Subgroup and
interaction analysis showed that the relationship between OBS and periodontitis was moderated by age with a stronger protective effect
of OBS observed in older participants age ≥ 65 years OR = 0. 61 95%CI = 0. 43-0. 87 . Conclusion This study indicates that an
increased OBS is associated with a reduced risk of periodontitis and this relationship is influenced by age. In older individuals a
higher OBS has a stronger protective effect against the risk of periodontitis. Improving OBS-related diet and lifestyle may help reduce
the occurrence and progression of periodontitis.
1Wang Zechen,2Wang Shanshan,3Liu Jingsi, et al. The relationship between oxidative balance score and periodontitis a study based on National Health and Nutrition
Examination Survey 2009-2012[J]. Electron J Metab Nutr Cancer, 2024, 11(5): 706-713.
