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| Advances and mechanisms of physical activity in cancer patients |
| Ren Qi, Zhang Fengmin, Zhuang Chengle |
| Department of Gastrointestinal Surgery Shanghai Tenth People ' s Hospital Shanghai 200072 China |
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Abstract The high mortality and poor prognosis of malignant tumors pose a serious threat to the postoperative health of cancer
patients. Traditional treatments such as surgery radiation therapy and chemotherapy remain essential yet patients still face risks of
tumor recurrence post-surgery alongside potential adverse effects on quality of life compromised physical functions and significant
anxiety and depression. In this context exercise therapy has emerged as one of the most accessible and convenient measures to improve
prognosis for cancer patients. Recent oncological rehabilitation guidelines frequently emphasize the importance of exercise
therapy. Physical activity enhances cardiorespiratory function and protein synthesis improves physiological skills and increases
physiological reserves. Moreover it helps regulate metabolism and immune balance creating an internal environment conducive to
combating tumors. Whether patients are in the perioperative period undergoing radiotherapy or chemotherapy or dealing with
conditions like cachexia or sarcopenia exercise therapy is a crucial rehabilitative approach. By selecting scientifically sound exercise
protocols and controlling appropriate frequency and intensity significant improvements in nutritional status can be achieved. This aids
patients in better completing their anti - tumor treatments reducing complications improving quality of life and even extending
survival. This review summarizes the clinical advancements of exercise therapy in cancer patients.
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