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| The relation of taste change nutritional status and cancer fatigue in lung cancer chemotherapy |
| 1Huang Wenxia,1Bai Qianwen,1Qian Jing,2Zhu Jie |
| 1Department of Oncology Suzhou Hospital of Traditional Chinese Medicine Suzhou 215008 Jiangsu China
2Blood Purification
Center Suzhou Hospital of Traditional Chinese Medicine Suzhou 215008 Jiangsu China |
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Abstract Objective To explore the correlation between taste change its nutritional status and cancer fatigue in lung cancer
chemotherapy patients. Method Retrospective analysis of 137 patients with lung cancer chemotherapy collected in Suzhou Hospital of
Traditional Chinese Medicine from February 2021 to February 2024 for chemotherapy-related taste change scale CiTAS nutritional
risk screening NRS 2002 cancer fatigue CFS status assessment Pearson method and linear regression analysis of CiTAS score
NRS 2002 score and CFS score. Result Basic taste change score 15. 52±2. 52 taste abnormalities and taste hallucinations 9. 12±
2. 63 eating distress 20. 15±2. 35 overall taste change 12. 35±2. 89 CiTAS score 57. 13±7. 78 NRS 2002 score 4. 89±
2. 22 physical fatigue 24. 86± 2. 84 emotional fatigue 12. 36± 2. 39 cognitive fatigue 11. 78± 2. 55 CFS score 49. 01±
6. 60 points. Analyzed by the Pearson method total score of CiTAS was positively correlated with NRS 2002 score physical fatigue
emotional fatigue cognitive fatigue and CFS total score After a linear regression analysis NRS 2002 The score and the total CiTAS
score will affect the total CFS score By the analysis of the mediation effect NRS 2002 Score β = 0. 469 P<0. 001 and total CiTAS
score β = 1. 105 P<0. 001 can significantly and positively predict the total CFS score The CiTAS total score plays a partial mediating
role in the influence of NRS 2002 score and CFS total score the mediation effect accounted for 21. 17% of the total effect
proportion. Conclusion Lung cancer chemotherapy patients taste change symptoms moderate to severe level and will directly affect the
nutrition and cancer fatigue taste change the more serious nutritional status cancer fatigue the more serious a positive correlation
to actively develop nutrition support adjust food taste to meet the demand of patients to ensure enough nutrition intake improve
physical and mental health.
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Received: 02 January 2024
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