Effects of enteral feeding through nasogastric tube on nutritional status and body status of patients with esophageal cancer
during radiotherapy and chemotherapy
1Department of Thoracic and Cardiac Surgery the First People's Hospital of Suqian Nanjing Medical University Suqian 223800
Jiangsu China
2Department of Oncology Suqian Hospital Nanjing Gulou Hospital Group Suqian 223800 Jiangsu
China
3Department of Oncology the First People's Hospital of Suqian Nanjing Medical University Suqian 223800 Jiangsu China
Abstract Objective To investigate the effects of intranasal feeding NGT through nasogastric tube on nutritional status and body
status of patients with esophageal cancer during radiotherapy and chemotherapy. Method Retrospective analysis was performed on 100
patients with esophageal cancer who underwent concurrent chemoradiation and chemotherapy treated in the First People's Hospital of
Suqian Affiliated to Nanjing Medical University from January 2020 to December 2023. They were divided into 2 groups according to
different nutritional therapy methods. The nutritional therapy methods were NGT enteral feeding n = 50 and oral nutritional
supplements ONS n = 50 . The nutritional status NRS 2002 and patient-generated subjective global assessment PG-SGA of the
two groups were compared before and after 8 weeks of intervention assessment PG-SGA body mass index BMI and related serum
nutritional indices body status Karnofsky performance status KPS and incidence of toxic side effects of chemoradiotherapy .
Result There was no significant difference in the scores of NRS 2002 PG-SGA and KPS between the two groups before intervention
P>0. 05 . After 8 weeks of intervention the scores of NRS 2002 and PG-SGA in NGT group were significantly lower than those in
ONS group while the scores of KPS in NGT group were significantly higher than those in ONS group P<0. 05 . Before intervention
there was no significant difference in serum nutritional indexes between the two groups P>0. 05 . After 8 weeks of intervention serum
ALb Hb Fer and prealbumin levels in NGT group were significantly higher than those in ONS group P< 0. 05 . There was no
significant difference in the incidence of toxicity and side effects between 2 groups P> 0. 05 . Conclusion Early NGT nutritional
support can effectively improve the nutritional status and physical status of patients with esophageal cancer receiving radiotherapy and
chemotherapy and has good clinical application value.
1Cheng Yanli,2Wang Miaomiao,3Zhong Huijuan, et al. Effects of enteral feeding through nasogastric tube on nutritional status and body status of patients with esophageal cancer
during radiotherapy and chemotherapy[J]. Electron J Metab Nutr Cancer, 2024, 11(4): 553-558.
